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http://hdl.handle.net/2445/69464| Title: | Insulin resistance compensation: not just a beta cell matter? |
| Author: | Montanya Mias, Eduard |
| Keywords: | Resistència a la insulina Illots de Langerhans Insulin resistance Islands of Langerhans |
| Issue Date: | 15-Mar-2014 |
| Publisher: | American Diabetes Association |
| Abstract: | The global epidemic of type 2 diabetes is largely secondary to insulin resistance induced by obesity and sedentary lifestyles. Most insulin-resistant subjects are able to increase b-cell secretion to meet the increased insulin demand and do not develop diabetes. However, when b-cell compensation fails, type 2 diabetes develops (1,2). Understanding the mechanisms of this compensatory response is of fundamental importance to elucidate the pathophysiology of type 2 diabetes and has implications for the treatment of the disease. |
| Note: | Reproducció del document publicat a: http://dx.doi.org/10.2337/db13-1843 |
| It is part of: | Diabetes, 2014, vol. 63, num. 3, p. 832-834 |
| URI: | http://hdl.handle.net/2445/69464 |
| Related resource: | http://dx.doi.org/10.2337/db13-1843 |
| ISSN: | 0012-1797 |
| Appears in Collections: | Articles publicats en revistes (Ciències Clíniques) |
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