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Title: Low prevalence of Cfr-mediated linezolid resistance among methicillin-resistant Staphylococcus aureus in a Spanish hospital: case report on linezolid resistance acquired during linezolid therapy
Author: Sierra, Josep M.
Camoez, Mariana
Tubau, Fe
Gasch, Oriol
Pujol Rojo, Miquel
Martin, Rogelio
Domínguez Luzón, Ma. Ángeles (María Ángeles)
Keywords: Staphylococcus aureus
Unitats de cures intensives
Infeccions respiratòries
Staphylococcus aureus
Intensive care units
Respiratory infections
Issue Date: 2013
Publisher: Public Library of Science (PLoS)
Abstract: Linezolid is an effective antimicrobial agent to treat methicillin-resistant Staphylococcus aureus (MRSA). Resistance to linezolid due to the cfr gene is described worldwide. The present study aimed to analyze the prevalence of the cfr-mediated linezolid resistance among MRSA clinical isolates in our area. A very low prevalence of cfr mediated linezolid resistance was found: only one bacteremic isolate out of 2 215 screened isolates. The only linezolid resistant isolate arose in a patient, previously colonized by MRSA, following linezolid therapy. Despite the low rate of resistance in our area, ongoing surveillance is advisable to avoid the spread of linezolid resistance.
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It is part of: PLoS One, 2013, vol. 8, num. 3
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ISSN: 1932-6203
Appears in Collections:Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))
Articles publicats en revistes (Patologia i Terapèutica Experimental)

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