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http://hdl.handle.net/2445/97365| Title: | Low prevalence of Cfr-mediated linezolid resistance among methicillin-resistant Staphylococcus aureus in a Spanish hospital: case report on linezolid resistance acquired during linezolid therapy |
| Author: | Sierra, Josep M. Camoez, Mariana Tubau, Fe Gasch, Oriol Pujol Rojo, Miquel Martín, Rogelio Domínguez Luzón, Ma. Ángeles (María Ángeles) |
| Keywords: | Staphylococcus aureus Unitats de cures intensives Infeccions respiratòries Staphylococcus aureus Intensive care units Respiratory infections |
| Issue Date: | 2013 |
| Publisher: | Public Library of Science (PLoS) |
| Abstract: | Linezolid is an effective antimicrobial agent to treat methicillin-resistant Staphylococcus aureus (MRSA). Resistance to linezolid due to the cfr gene is described worldwide. The present study aimed to analyze the prevalence of the cfr-mediated linezolid resistance among MRSA clinical isolates in our area. A very low prevalence of cfr mediated linezolid resistance was found: only one bacteremic isolate out of 2 215 screened isolates. The only linezolid resistant isolate arose in a patient, previously colonized by MRSA, following linezolid therapy. Despite the low rate of resistance in our area, ongoing surveillance is advisable to avoid the spread of linezolid resistance. |
| Note: | Reproducció del document publicat a: http://dx.doi.org/10.1371/journal.pone.0059215 |
| It is part of: | PLoS One, 2013, vol. 8, num. 3 |
| URI: | http://hdl.handle.net/2445/97365 |
| Related resource: | http://dx.doi.org/10.1371/journal.pone.0059215 |
| ISSN: | 1932-6203 |
| Appears in Collections: | Articles publicats en revistes (Patologia i Terapèutica Experimental) Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
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