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http://hdl.handle.net/2445/99399
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DC Field | Value | Language |
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dc.contributor.author | Ballette, Roberto | - |
dc.contributor.author | Pérez Bosch, Maria | - |
dc.contributor.author | Proto, Stefano | - |
dc.contributor.author | Amat Tusón, Mercedes | - |
dc.contributor.author | Bosch Cartes, Joan | - |
dc.date.accessioned | 2016-06-09T17:21:14Z | - |
dc.date.available | 2016-06-09T17:21:14Z | - |
dc.date.issued | 2014-05-02 | - |
dc.identifier.issn | 1433-7851 | - |
dc.identifier.uri | http://hdl.handle.net/2445/99399 | - |
dc.description.abstract | Madangamines are a group of bioactive marine sponge alkaloids, embodying an unprecedented diazapentacyclic skeletal type. The enantioselective total synthesis of madangamine D has been accomplished, and represents the first total synthesis of an alkaloid of the madangamine group. It involves the stereoselective construction of the diazatricyclic ABC core using a phenylglycinol-derived lactam as the starting enantiomeric scaffold and the subsequent assembly of the peripheral macrocyclic rings. The synthesis provides, for the first time, a pure sample of madangamine D and confirms the absolute configuration of this alkaloid family. | - |
dc.format.extent | 4 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Wiley-VCH | - |
dc.relation.isformatof | Versió postprint del document publicat a: http://dx.doi.org/10.1002/anie.201402263 | - |
dc.relation.ispartof | Angewandte Chemie-International Edition, 2014, vol. 53, num. 24, p. 6202-6205 | - |
dc.relation.uri | http://dx.doi.org/10.1002/anie.201402263 | - |
dc.rights | (c) Wiley-VCH, 2014 | - |
dc.source | Articles publicats en revistes (Nutrició, Ciències de l'Alimentació i Gastronomia) | - |
dc.subject.classification | Farmacologia | - |
dc.subject.classification | Esponges | - |
dc.subject.classification | Alcaloides | - |
dc.subject.classification | Productes naturals marins | - |
dc.subject.other | Pharmacology | - |
dc.subject.other | Sponges | - |
dc.subject.other | Alkaloids | - |
dc.subject.other | Marine natural products | - |
dc.title | Total Synthesis of (+)-Madangamine D | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/acceptedVersion | - |
dc.identifier.idgrec | 642020 | - |
dc.date.updated | 2016-06-09T17:21:19Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 24798407 | - |
Appears in Collections: | Articles publicats en revistes (Nutrició, Ciències de l'Alimentació i Gastronomia) |
Files in This Item:
File | Description | Size | Format | |
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642020.pdf | 699.08 kB | Adobe PDF | View/Open |
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