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Title: Carriage prevalence of Salmonella enterica serotype Typhi in gallbladders of adult autopsy cases from Mozambique
Author: Lovane, Lucilia
Martínez Yoldi, Miguel Julián
Massora, Sérgio
Mandomando, Inácio
Ussene, Esperança
Jordão, Dercio
Castillo, Paola
Ismail, Mamudo R.
Lorenzoni, Cesaltina
Carrilho, Carla
Bassat Orellana, Quique
Menéndez, Clara
Ordi i Majà, Jaume
Vila Estapé, Jordi
Soto, Sara M. (Sara Maria)
Keywords: Salmonel·la
Issue Date: Apr-2016
Publisher: The Journal of Infection in Developing Countries
Abstract: INTRODUCTION: Typhoid fever is an important public health problem in many low-income countries where asymptomatic carriers play an important role in its dissemination. The bacterium causing typhoid fever can live in the gallstones of asymptomatic persons after the infection. These carriers are reservoirs of S. Typhi, are highly contagious, and spread the disease through the secretion of bacteria in feces and urine. The aim of this study was to determine the carrier rate in an area of Mozambique. METHODOLOGY: The presence of S. Typhi was analyzed in gallbladder samples obtained from 99 adult corpses (in-hospital deaths) from Mozambique by gold-standard culture and polymerase chain reaction (PCR). RESULTS: Only one sample was positive with the culture. However, nine additional samples were positive by PCR and confirmed by DNA sequencing. Thus, the prevalence of S. Typhi was 10.1% (10/99). CONCLUSIONS: We report a high prevalence of S. Typhi in gallbladders among adult autopsy cases from Mozambique.
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It is part of: Journal of Infection in Developing Countries, 2016, vol. 10, num. 4, p. 410-412
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ISSN: 1972-2680
Appears in Collections:Articles publicats en revistes (ISGlobal)
Articles publicats en revistes (Fonaments Clínics)

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