Please use this identifier to cite or link to this item: http://hdl.handle.net/2445/99581
Title: Delayed haemolysis after artesunate therapy in a cohort of patients with severe imported malaria due to Plasmodium falciparum
Author: Gómez-Junyent, J.
Ruiz-Panales, P.
Calvo-Cano, Antonia
Gascón i Brustenga, Joaquim
Muñoz, José
Keywords: Malària
Plasmodium falciparum
Malaria
Plasmodium falciparum
Issue Date: 23-Dec-2015
Publisher: Elsevier España
Abstract: INTRODUCTION: Delayed haemolytic anaemia is one of the more frequent events after treatment with intravenous artesunate in patients with severe malaria. Little is known about its frequency and the outcomes of patients with this condition. METHODS: A retrospective study was conducted to describe the incidence of delayed haemolysis in a cohort of patients with severe malaria by Plasmodium falciparum treated with artesunate between August 2013 and July 2015. RESULTS: The study included 52 patients with malaria due to Plasmodium falciparum, with 21 having severe malaria. The majority were male (66.7%), and the median age was 43 years. Four patients (19%) presented post-artesunate delayed haemolysis 11-13 days from the initiation of treatment. Two patients required hospital admission and red blood cell transfusion. CONCLUSION: Post-artesunate delayed haemolysis is frequent in patients with severe malaria treated with intravenous artemisinins. These patients should be monitored for 4 weeks after treatment is started.
Note: Versió postprint del document publicat a: http://dx.doi.org/10.1016/j.eimc.2015.11.003
It is part of: Enfermedades Infecciosas y Microbiologia Clinica, 2016
Related resource: http://dx.doi.org/10.1016/j.eimc.2015.11.003
URI: http://hdl.handle.net/2445/99581
ISSN: 0213-005X
Appears in Collections:Articles publicats en revistes (ISGlobal)

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