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Title: Real-Time Polymerase Chain Reaction in Stool Detects Transmission of Strongyloides stercoralis from an Infected Donor to Solid Organ Transplant Recipients
Author: Gómez-Junyent, Joan
Paredes-Zapata, David
Rodríguez de las Parras, Esperanza
González-Costello, José
Ruiz-Arranz, Ángel
Cañizares, Rosario
Saugar, José María
Muñoz, José
Keywords: Malalties parasitàries
Trasplantament d'òrgans
Parasitic diseases
Transplantation of organs
Issue Date: 15-Feb-2016
Publisher: American Society of Tropical Medicine and Hygiene
Abstract: Solid organ transplant recipients can acquire Strongyloides stercoralis from an infected donor. The diagnosis of S. stercoralis in immunocompromised individuals may be challenging due to a lower sensitivity of available parasitological and serological methods, compared with immunocompetent individuals. Recently, a real-time polymerase chain reaction (RT-PCR) in stool has been developed for S. stercoralis diagnosis. We report two cases of S. stercoralis infection transmitted by a donor to two solid organ transplant recipients, whose stool samples were diagnosed using RT-PCR. This test could play an important role in S. stercoralis diagnosis in immunosuppressed patients, facilitating rapid treatment initiation and reducing the risk of severe strongyloidiasis. Adherence to current recommendations of screening among donors and recipients from endemic areas is also urgently needed.
Note: Versió postprint del document publicat a:
It is part of: American Journal of Tropical Medicine and Hygiene, 2016, vol. 94, num. 4, p. 897-899
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ISSN: 0002-9637
Appears in Collections:Articles publicats en revistes (ISGlobal)

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