Browsing by Subject Drug targeting
Showing results 1 to 20 of 55
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| Issue Date | Title | Author(s) |
|---|---|---|
| 23-Oct-2018 | A computationally designed binding mode flip leads to a novel class of potent tri-vector cyclophilin inhibitors | De Simone, Alessio; Georgiou, Charis; Ioannidis, Harris; Gupta, Arun A.; Juárez-Jiménez, Jordi; Doughty-Shenton, Dahlia; Blackburn, Elizabeth A.; Wear, Martin A.; Richards, Jonathan P.; Barlow, Paul N.; Carragher, Neil; Walkinshaw, Malcolm D.; Hulme, Alison N.; Michel, Julien |
| 2-Jul-2022 | Aberrant TIMP-1 overexpression in tumor-associated fibroblasts drives tumor progression through CD63 in lung adenocarcinoma | Duch, Paula; Díaz Valdivia, Natalia; Ikemori, Rafael; Gabasa Ferràndez, Marta; Radisky, Evette S; Arshakyan, Marselina; Gea Sorli, Sabrina; Mateu Bosch, Anna; Bragado Domingo, Paloma; Carrasco, Josep Lluís; Mori, Hidetoshi; Ramírez Ruz, J. (José); Teixidó, Cristina; Reguart, Noemí; Fillat i Fonts, Cristina; Radisky, Derek C; Alcaraz Casademunt, Jordi |
| 7-Feb-2025 | Addressing Alzheimer's disease through innovative mechanisms | Martínez Conde, Noemí |
| 18-Sep-2020 | Chemical Probes for Blocking of Influenza A M2 Wild-type and S31N Channels | Tzitzoglaki, Christina; McGuire, Kelly; Lagarias, Panagiotis; Konstantinidi, Athina; Hoffmann, Anja; Fokina, Natalie A.; Ma, Chulong; Papanastasiou, Ioannis P.; Schreiner, Peter R.; Vázquez Cruz, Santiago; Schmidtke, Michaela; Wang, Jun; Busath, David D.; Kolocouris, Antonios |
| 24-May-2016 | Combatent el virus de la Influenza. Noves estructures i dianes terapèutiques (Seminaris de Recerca 2016) | Barniol-Xicota, Marta; Torres Costa, Eva; Leiva Martínez, Rosana; Rey Carrizo, Matías; Vázquez Cruz, Santiago |
| 5-Oct-2012 | Combined drug action of 2-phenylimidazo[2,1-b]benzothiazole derivatives on cancer cells according to their oncogenic molecular signatures | Furlan, Alessandro; Roux, Benjamin; Lamballe, Fabienne; Conti, Filippo; Issaly, Nathalie; Daian, Fabrice; Guillemot, Jean-François; Richelme, Sylvie; Contensin, Magali; Bosch Cartes, Joan; Passarella, Daniele; Piccolo, Oreste; Dono, Rosanna; Maina, Flavio |
| 2-May-2013 | Combined use of NMR and computational tools for fragment based drug discovery targeting protein-protein interactions VEGF protein surface recognition as a case study | Goldflam, Michael |
| 6-Sep-2021 | Complejos del receptor sigma y de heterómeros de receptores acoplados a proteínas G en adicción y control de apetito | Casanovas Ferrero, Mireia |
| 19-Mar-2013 | Conjugation of a Ru(II) Arene Complex to Neomycin or to Guanidinoneomycin Leads to Compounds with Differential Cytotoxicities and Accumulation between Cancer and Normal Cells | Grau Campistany, Ariadna; Massaguer i Vall-llovera, Anna; Carrión-Salip, Dolors; Barragán, Flavia; Artigas Solé, Gerard; López-Senín, Paula; Moreno Martínez, Virtudes; Marchán Sancho, Vicente |
| 9-Jul-2010 | Consecuencias clínicas de la persistencia de actividad inflamatoria en la arteritis de células gigantes. Estudio de factores implicados | García Martínez, Ana |
| 24-Jan-2013 | Desenvolupament de lligands de l’estructura secundària d’RNA implicada en el processat alternatiu de l’exó 10 de la proteïna tau | Artigas Solé, Gerard |
| 24-Jul-2020 | Design and synthesis of heterocyclic compounds potentially antitumor by enzymatic inhibition | Lizano Gispert, Enric |
| 2-Dec-2022 | Design of peptides able to modulate Protein-protein interactions (PPIs) in mutated p53 | Nicolini, Federica |
| 1-Jul-2025 | Development and application of computational methodologies for novel therapeutic strategies based on protein-protein interactions | Díaz Rovira, Anna Maria |
| 20-Sep-2021 | Development and characterization of in vivo models for Photopharmacology | Gomila Juaneda, Alexandre |
| 19-Apr-2016 | Epigenetic alterations leading to TMPRSS4 promoter hypomethylation and protein overexpression predict poor prognosis in squamous lung cancer patients | Villalba, Maria; Diaz-Lagares, Angel; Redrado, Miriam; Aberasturi, Arrate L. de; Segura, Victor; Bodegas, Maria Elena; Pajares, María José; Pio, Ruben; Freire, Javier; Gomez-Roman, Javier; Montuenga, Luis M.; Esteller, Manel; Sandoval, Juan; Calvo, Alfonso |
| 1-Oct-2021 | Exploring molecular mechanisms of key targets in metabolic and infectious diseases | Aledavood, Elnaz |
| 25-Apr-2025 | Exploring novel target combinations for treating neurodegenerative diseases | Sampietro Pifarré, Anna |
| 2012 | Exploring the effect of aminoglycoside guanidinylation on ligands for Tau exon 10 splicing regulatory element RNA | López-Senín, Paula; Artigas Solé, Gerard; Marchán Sancho, Vicente |
| 14-Nov-2008 | Expressió de KIT i PDGFR en tumors de cèl·lules renals. Discussió del seu paper com a possibles dianes terapèutiques | Petit Montserrat, Ana |