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http://hdl.handle.net/2445/100564
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DC Field | Value | Language |
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dc.contributor.author | Bassat Orellana, Quique | - |
dc.contributor.author | Lanaspa, Miguel | - |
dc.contributor.author | Machevo, Sonia | - |
dc.contributor.author | O'Callaghan Gordo, Cristina | - |
dc.contributor.author | Madrid, Lola | - |
dc.contributor.author | Nhampossa, Tacilta | - |
dc.contributor.author | Acácio, Sozinho | - |
dc.contributor.author | Roca, A. | - |
dc.contributor.author | Alonso, Pedro | - |
dc.date.accessioned | 2016-07-18T08:03:13Z | - |
dc.date.available | 2017-07-11T22:01:42Z | - |
dc.date.issued | 2016-07-11 | - |
dc.identifier.issn | 1360-2276 | - |
dc.identifier.uri | http://hdl.handle.net/2445/100564 | - |
dc.description.abstract | OBJECTIVE: To determine the prevalence of hypoxaemia among under-five children admitted to hospital with clinical severe pneumonia, and to assess the performance to diagnose hypoxaemia of models based on clinical signs. METHODS: We conducted a hospital-based survey in a district hospital from Southern Mozambique. RESULTS: A total of 825 children were recruited after obtaining an informed consent. The prevalence of hypoxaemia on admission was 27.9%, and 19.8% of these children died (OR compared to non-hypoxaemic children 3.22, 95%CI 1.98 - 5.21, p<0.001). The model with larger area under the ROC curve (AUC-ROC) to predict hypoxaemia included cyanosis or thoracoabdominal breathing or respiratory rate >/= 70 breaths per minute. None of the models performed well when tested in different case scenarios of oxygen availability through mathematical modelling, with over 50% of hypoxaemic children not receiving oxygen even in favourable case scenarios. CONCLUSIONS: Clinical signs alone or in combination are not suitable to diagnose hypoxaemia. The use of pulse oximeters should be strongly encouraged. This article is protected by copyright. All rights reserved. | - |
dc.format.extent | 26 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Wiley Online Library | - |
dc.relation.isformatof | Versió postprint del document publicat a: http://dx.doi.org/10.1111/tmi.12738 | - |
dc.relation.ispartof | Tropical Medicine & International Health, 2016 | - |
dc.relation.uri | http://dx.doi.org/10.1111/tmi.12738 | - |
dc.rights | (c) Wiley Online Library, 2016 | - |
dc.source | Articles publicats en revistes (ISGlobal) | - |
dc.subject.classification | Infants | - |
dc.subject.classification | Pneumònia | - |
dc.subject.classification | Moçambic | - |
dc.subject.other | Children | - |
dc.subject.other | Pneumonia | - |
dc.subject.other | Mozambique | - |
dc.title | Hypoxaemia in Mozambican children < 5 years of age admitted to hospital with clinical severe pneumonia: clinical features and performance of predictor models | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/acceptedVersion | - |
dc.date.updated | 2016-07-01T10:21:25Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
Appears in Collections: | Articles publicats en revistes (ISGlobal) |
Files in This Item:
File | Description | Size | Format | |
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bassat2016_2157.pdf | 812.04 kB | Adobe PDF | View/Open |
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