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Title: | Aortic intima-media thickness and aortic diameter in small for gestational age and growth restricted fetuses |
Author: | Gómez Roig, Ma. Dolores Mazarico Gallego, Edurne Valladares, Esther Guirado, Laura Fernandez-Arias, Mireia Vela Martínez, Antonio |
Keywords: | Fetus Aorta Malalties cardiovasculars Antropometria Creixement fetal Aterosclerosi Estudi de casos Fetus Aorta Cardiovascular diseases Anthropometry Fetal growth Atherosclerosis Case studies |
Issue Date: | 27-May-2015 |
Publisher: | Public Library of Science (PLoS) |
Abstract: | Abstract OBJECTIVE: The objective of this study is to measure aortic intima-media thickness (aIMT) and aortic diameter (AD) in appropriate for gestational age (AGA) fetuses, small for gestational age (SGA) fetuses, and intrauterine growth restricted (IUGR) fetuses. METHODS: Case-control study performed between June 2011 and June 2012. Forty-nine AGA fetuses, 40 SGA fetuses, and 35 IUGR fetuses underwent concomitant measurement of aIMT and AD at a mean gestational age of 34.4 weeks. RESULTS: Median aIMT was higher in fetuses with IUGR (0.504 mm [95%CI: 0.477-0.530 mm]), than in SGA fetuses (0.466 mm [95% CI: 0.447-0.485 mm]), and AGA fetuses (0.471 mm [95% CI: 0.454-0.488 mm]) (p = 0.023). Mean AD was significantly lower in fetuses with IUGR (4.451 mm [95% CI: 4.258-4.655 mm]), than in AGA fetuses (4.74 mm [95% CI: 4.63-4.843 mm]) (p = 0.028). CONCLUSIONS: Growth restricted fetuses have a thicker aortic wall than AGA and SGA fetuses, which possibly represents preclinical atherosclerosis and a predisposition to later cardiovascular disease. |
Note: | Reproducció del document publicat a: http://dx.doi.org/10.1371/journal.pone.0126842 |
It is part of: | PLoS One, 2015, vol. 10, num. 5, p. e0126842 |
URI: | http://hdl.handle.net/2445/102727 |
Related resource: | http://dx.doi.org/10.1371/journal.pone.0126842 |
ISSN: | 1932-6203 |
Appears in Collections: | Articles publicats en revistes (Ciències Clíniques) |
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