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Title: Invasive pneumococcal disease in children: Risk factors and vaccine effectiveness
Author: Ciruela, Pilar
Soldevila, Núria
Izquierdo, Conchita
Hernández, Sergi
Domínguez García, Àngela
Keywords: Infeccions per pneumococs
Salut pública
Mortalitat infantil
Pneumococcal Infections
Public health
Infant mortality
Issue Date: 2016
Publisher: Research Signpost
Abstract: Invasive pneumococcal disease (IPD) has high morbidity and mortality worldwide. The overall incidence of IPD in Catalonia in 2005-2009 was 16.6 per 100,000 persons-year, 66.4 in children aged < 2 years and 50.7 in children aged 2-4 years. 7-valent pneumococcal conjugate vaccine (PCV7) coverage in Catalonia is intermediate. A prospective matched case-control study in children aged 3-59 months treated at two hospitals in Catalonia during 2007-2009 was performed. Potential risk factors for IPD and PCV7 effectiveness in preventing IPD were investigated. 293 cases and 785 controls were included. Attendance at daycare or school was a risk factor for IPD (aOR 3.07, 95% CI 1.97-4.78) and the effectiveness of PCV7 against vaccine serotypes was 93.7% (95% CI 51.8 -99.2).
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It is part of: Recent Advances in Pharmaceutical Sciences VI, 2016, Research Signpost. Editors: Diego Muñoz Torrero, Àngela Domínguez García & Ma. Ángeles Manresa Presas. ISBN: 978-81-308-0566-5. Chapter 6, p. 91-110.
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Appears in Collections:Llibres / Capítols de llibre (Medicina)

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