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http://hdl.handle.net/2445/104863
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DC Field | Value | Language |
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dc.contributor.author | Amat Tusón, Mercedes | - |
dc.contributor.author | Llor Brunés, Núria | - |
dc.contributor.author | Guignard, Guillaume Michel Pablo | - |
dc.contributor.author | Bosch Cartes, Joan | - |
dc.date.accessioned | 2016-12-19T12:53:40Z | - |
dc.date.available | 2016-12-19T12:53:40Z | - |
dc.date.issued | 2016-06-23 | - |
dc.identifier.issn | 0328-1205 | - |
dc.identifier.uri | http://hdl.handle.net/2445/104863 | - |
dc.description.abstract | Fluvirucins are bioactive macrolactam glycosides isolated from actinomycetes. This review gives an overview of this family of natural products, covering isolation, biological activities, biosynthesis, and total synthesis. The synthesis of fluvirucins and their aglycons, the fluvirucinins, is presented, paying special attention to the synthetic strategy and stereochemical aspects. 1 Introduction 2 Isolation, Biological Activity, and Biosynthesis 3 Synthetic Approaches 3.1 Closure of the 14-Membered Ring by Ring-Closing Metathesis 3.2 Closure of the 14-Membered Ring by Macrolactamization 3.3 Construction of the 14-Membered Ring by Aza-Claisen Ring Expansion 4 Conclusion | - |
dc.format.extent | 16 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Universidad Nacional de La Plata | - |
dc.relation.isformatof | Reproducció del document publicat a: https://doi.org/10.1055/s-0035-1561469 | - |
dc.relation.ispartof | Synthesis, 2016, vol. 48, num. 17, p. 2705-2720 | - |
dc.relation.uri | https://doi.org/10.1055/s-0035-1561469 | - |
dc.rights | cc-by-nc-nd (c) Amat Tusón, Mercedes et al., 2016 | - |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/es | - |
dc.source | Articles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica) | - |
dc.subject.classification | Lactames | - |
dc.subject.classification | Glucòsids | - |
dc.subject.other | Lactams | - |
dc.subject.other | Glucosides | - |
dc.title | Synthesis of fluvirucins and their aglycons, the fluvirucinins | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.identifier.idgrec | 662823 | - |
dc.date.updated | 2016-12-19T12:53:45Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
Appears in Collections: | Articles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica) |
Files in This Item:
File | Description | Size | Format | |
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662823.pdf | 982.99 kB | Adobe PDF | View/Open |
This item is licensed under a Creative Commons License