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http://hdl.handle.net/2445/105108
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DC Field | Value | Language |
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dc.contributor.author | Valle Delgado, Juan José | - |
dc.contributor.author | Fernàndez Busquets, Xavier | - |
dc.date.accessioned | 2016-12-22T11:05:44Z | - |
dc.date.available | 2017-10-18T22:01:25Z | - |
dc.date.issued | 2016-10-18 | - |
dc.identifier.issn | 1746-0913 | - |
dc.identifier.uri | http://hdl.handle.net/2445/105108 | - |
dc.description.abstract | Prompt and accurate diagnosis of malaria is part of an effective disease management (1) , because if not treated malaria can quickly become life-threatening, whereas false positives increase treatment costs and drug-induced resistance, giving a wrong idea of therapeutic efficacy. Since the symptoms of malaria are nonspecific, the observation of clinical features alone might not be enough and should be confirmed with a parasitological analysis. Microscopic examination of Giemsa-stained thin and/or thick blood smears remains the conventional approach for diagnosis (2). The sensitivity of this relatively inexpensive method is excellent, allowing the detection of as few as 5 parasites per µL of blood, and permitting also the determination of the infecting species and of the developmental stage of circulating parasites. In addition, smears provide a permanent record for quality assessment of the diagnosis. However, microscopy requires considerable expertise learned through extended training, the procedure is labor-intensive and time-consuming, and the variability in stains and in techniques used to collect and process blood affects slide interpretation (3). Finally, routine clinical microscopy cannot reliably detect very low parasitemias (<5 parasites/µL) or sequestered parasites, and mixed infections are often missed, especially when Plasmodium malariae and Plasmodium ovale are present, as their densities are often low relative to Plasmodium falciparum ( | - |
dc.format.extent | 10 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Future Medicine | - |
dc.relation.isformatof | Versió postprint del document publicat a: http://dx.doi.org/10.2217/fmb-2016-0139 | - |
dc.relation.ispartof | Future Microbiology, 2016, vol. 11, num. 11, p. 1379-1382 | - |
dc.relation.uri | http://dx.doi.org/10.2217/fmb-2016-0139 | - |
dc.rights | (c) Future Medicine, 2016 | - |
dc.source | Articles publicats en revistes (ISGlobal) | - |
dc.subject.classification | Malària | - |
dc.subject.classification | Diagnòstic | - |
dc.subject.other | Malaria | - |
dc.subject.other | Diagnosis | - |
dc.title | Rapid diagnostic tests for malaria: past, present and future | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/acceptedVersion | - |
dc.date.updated | 2016-12-21T19:00:25Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 27750453 | - |
Appears in Collections: | Articles publicats en revistes (ISGlobal) |
Files in This Item:
File | Description | Size | Format | |
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valle-delgado2016_2281.pdf | 126.88 kB | Adobe PDF | View/Open |
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