Please use this identifier to cite or link to this item:
Full metadata record
DC FieldValueLanguage
dc.contributor.authorMalvehy, J. (Josep)-
dc.contributor.authorRoldán-Marín, Rodrigo-
dc.contributor.authorIglesias-García, Pablo-
dc.contributor.authorDíaz Lorca, Maria Alba-
dc.contributor.authorPuig i Sardà, Susana-
dc.description.abstractVisual inspection may fail to accurately evaluate field cancerisation (subclinical actinic keratoses [AKs]). We aimed to describe field cancerisation by confocal reflectance microscopy and changes induced by the application of 3% diclofenac sodium gel in 2.5% hyaluronic acid. Fourteen male patients, > 50 years old, with AKs on the bald scalp were included. Clinical examination, confocal microscopy and histological study of clinically visible lesions and 'normal appearing' adjacent skin before and after treatment was completed. Reflectance confocal microscopy showed a decrease in scaling (p = 0.001) and atypia of the honeycomb pattern (p = 0.001) at 2 weeks of treatment. Changes in parakeratosis, inflammation and dermal collagen remodelling were also observed. Histology correlated with confocal features in AK and subclinical AK. Reflectance confocal microscopy was useful in the evaluation of field cancerisation and monitoring of treatment response. A rapid improvement in epidermal atypia was observed.-
dc.format.extent6 p.-
dc.publisherSociety for the Publication of Acta Dermato-Venereologica-
dc.relation.isformatofReproducció del document publicat a:
dc.relation.ispartofActa Dermato-Venereologica, 2014, vol. 95, num. 1, p. 45-50-
dc.rights(c) Malvehy, J. (Josep) et al., 2014-
dc.subject.classificationMalalties de la pell-
dc.subject.classificationCàncer de pell-
dc.subject.otherSkin diseases-
dc.subject.otherSkin cancer-
dc.titleMonitoring treatment of field cancerisation with 3% diclofenac sodium 2.5% hyaluronic acid by reflectance confocal microscopy: a histologic correlation-
Appears in Collections:Articles publicats en revistes (Medicina)
Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer)
Articles publicats en revistes (Fonaments Clínics)

Files in This Item:
File Description SizeFormat 
642109.pdf2.71 MBAdobe PDFView/Open

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.