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Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/110580
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dc.contributor.authorGarcía Pindado, Júlia-
dc.contributor.authorRoyo, Soledad-
dc.contributor.authorTeixidó Turà, Meritxell-
dc.contributor.authorGiralt Lledó, Ernest-
dc.date.accessioned2017-05-08T12:35:56Z-
dc.date.available2018-03-16T23:01:20Z-
dc.date.issued2017-03-16-
dc.identifier.issn1075-2617-
dc.identifier.urihttps://hdl.handle.net/2445/110580-
dc.description.abstractSeveral natural peptides have a biaryl or biaryl ether motif in their biologically active structures. A model bicyclic pentapeptide containing a biaryl bridge has been synthesized by solid-phase peptide synthesis combining on-resin Suzuki and Miyaura cross-coupling reactions. Its biological properties in terms of permeability, stability and cytotoxicity have been studied, demon-strating the positive contribution of the biaryl bridge, excellent membrane penetration and serum stabilityeng
dc.format.extent9 p.-
dc.format.mimetypeapplication/pdf-
dc.language.isoeng-
dc.publisherJohn Wiley & Sons-
dc.relation.isformatofVersió postprint del document publicat a: http://dx.doi.org/10.1002/psc.2993-
dc.relation.ispartofJournal of Peptide Science, 2017, vol. 23, num. 4, p. 294-302-
dc.relation.urihttp://dx.doi.org/10.1002/psc.2993-
dc.rights(c) European Peptide Society and John Wiley & Sons, 2017-
dc.sourceArticles publicats en revistes (Institut de Recerca Biomèdica (IRB Barcelona))-
dc.subject.classificationSíntesi de pèptidscat
dc.subject.classificationProductes naturalscat
dc.subject.classificationSíntesi orgànicacat
dc.subject.otherPeptide synthesiseng
dc.subject.otherNatural productseng
dc.subject.otherOrganic synthesiseng
dc.titleBike peptides: a ride through the membrane-
dc.typeinfo:eu-repo/semantics/article-
dc.typeinfo:eu-repo/semantics/acceptedVersion-
dc.date.updated2017-05-08T12:25:05Z-
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess-
Appears in Collections:Articles publicats en revistes (Química Inorgànica i Orgànica)
Articles publicats en revistes (Institut de Recerca Biomèdica (IRB Barcelona))

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