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http://hdl.handle.net/2445/110712
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DC Field | Value | Language |
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dc.contributor.author | Gandioso, Albert | - |
dc.contributor.author | Massaguer i Vall-llovera, Anna | - |
dc.contributor.author | Villegas, Núria | - |
dc.contributor.author | Salvans, Cándida | - |
dc.contributor.author | Sánchez, Dani | - |
dc.contributor.author | Brun-Heath, Isabelle | - |
dc.contributor.author | Marchán Sancho, Vicente | - |
dc.contributor.author | Orozco López, Modesto | - |
dc.contributor.author | Terrazas Martínez, Montserrat | - |
dc.date.accessioned | 2017-05-09T13:25:52Z | - |
dc.date.available | 2018-12-31T06:10:19Z | - |
dc.date.issued | 2017-02-13 | - |
dc.identifier.issn | 1359-7345 | - |
dc.identifier.uri | http://hdl.handle.net/2445/110712 | - |
dc.description.abstract | Despite the broad applicability of the Huisgen cycloaddition reaction, the click functionalization of RNAs with peptides remains still a challenge. Here we describe a straightforward method for the click functionalization of siRNAs with peptides of different size and complexity. Among them, a promising peptide carrier for the selective siRNA delivery into HER2+ breast cancer cell lines. | - |
dc.format.extent | 4 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Royal Society of Chemistry | - |
dc.relation.isformatof | Versió postprint del document publicat a: https://doi.org/10.1039/C6CC10287E | - |
dc.relation.ispartof | Chemical Communications, 2017, vol. 53, num. 19, p. 2870-2873 | - |
dc.relation.uri | https://doi.org/10.1039/C6CC10287E | - |
dc.rights | (c) Gandioso et al., 2017 | - |
dc.subject.classification | RNA | - |
dc.subject.classification | Pèptids | - |
dc.subject.classification | Càncer de mama | - |
dc.subject.classification | Cèl·lules canceroses | - |
dc.subject.other | RNA | - |
dc.subject.other | Peptides | - |
dc.subject.other | Breast cancer | - |
dc.subject.other | Cancer cells | - |
dc.title | Efficient siRNA-peptide conjugation for specific targeted delivery into tumor cells | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/acceptedVersion | - |
dc.identifier.idgrec | 667552 | - |
dc.date.updated | 2017-05-09T13:25:52Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
Appears in Collections: | Articles publicats en revistes (Química Inorgànica i Orgànica) Articles publicats en revistes (Institut de Recerca Biomèdica (IRB Barcelona)) |
Files in This Item:
File | Description | Size | Format | |
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667552.pdf | 1.24 MB | Adobe PDF | View/Open |
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