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http://hdl.handle.net/2445/114190
Title: | Respiratory microbiota and lower respiratory tract disease |
Author: | Lanaspa, Miguel Bassat Orellana, Quique Medeiros, Marcia Melo Muñoz-Almagro, Carmen |
Keywords: | Malalties de l'aparell respiratori Bacteris Respiratory organs diseases Bacteria |
Issue Date: | 7-Jul-2017 |
Publisher: | Taylor & Francis |
Abstract: | INTRODUCTION: The respiratory airways harbor a complex succession of ecological niches with distinct but related bacterial communities. Particular challenges of respiratory microbiome research have led to limited scientific output compared to other human microbiomes. Areas covered: In this review, we summarize the current state of knowledge of the bacterial respiratory microbiome, with a particular focus on associations between the respiratory microbiome and lower respiratory tract conditions. Expert commentary: There is growing evidence that the respiratory microbiome is associated with lower respiratory infectious diseases and related conditions. Most respiratory microbiome reports are metataxonomic cross-sectional or case-control studies with relatively small sample sizes. Large, prospective projects with metatranscriptomics or metabolomics approach are needed to unravel the effect of the respiratory microbiome on health-related conditions. Moreover, standardization in sampling, library preparation, sequencing techniques and data analysis should be encouraged. |
Note: | Reproducció del document publicat a: http://dx.doi.org/10.1080/14787210.2017.1349609 |
It is part of: | Expert Review of Anti-Infective Therapy, 2017, vol. 15, num. 7, p. 703-711 |
URI: | http://hdl.handle.net/2445/114190 |
Related resource: | http://dx.doi.org/10.1080/14787210.2017.1349609 |
ISSN: | 1478-7210 1478-7210 |
Appears in Collections: | Articles publicats en revistes (ISGlobal) |
Files in This Item:
File | Description | Size | Format | |
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lanaspa2017_2597.pdf | 353.89 kB | Adobe PDF | View/Open |
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