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http://hdl.handle.net/2445/116084| Title: | Voltammetric determination of antihypertensive drug hydrochlorothiazide using screen-printed electrodes modified with L- glutamic acid |
| Author: | González-Vargas, Camilo Serrano i Plana, Núria Ariño Blasco, Cristina Salazar, Ricardo Esteban i Cortada, Miquel Díaz Cruz, José Manuel |
| Keywords: | Anàlisi electroquímica Voltametria Electrochemical analysis Voltammetry |
| Issue Date: | 17-Sep-2017 |
| Publisher: | MDPI |
| Abstract: | This work deals with the development of screen-printed carbon electrodes modified with L-glutamic acid via two different approaches: electropolymerization (SPCE/PGA) and aryl diazonium electrochemical grafting (SPCE/EGA). SPCE/PGA and SPCE/EGA were analytically compared in the determination of hydrochlorothiazide (HCTZ) by differential pulse voltammetry. Both electrochemical characterization and analytical performance indicate that SPCE/EGA is a much better sensor for HCTZ. The detection and quantification limits were at the level of micromol L-1 with a very good linearity in the studied concentration range. In addition, the proposed SPCE/EGA was successfully applied for the determination of HCTZ in an anti-hypertensive drug with high reproducibility and good trueness. |
| Note: | Reproducció del document publicat a: https://doi.org/10.3390/chemosensors5030025 |
| It is part of: | Chemosensors, 2017, vol. 5, num. 25, p. 1-12 |
| URI: | http://hdl.handle.net/2445/116084 |
| Related resource: | https://doi.org/10.3390/chemosensors5030025 |
| ISSN: | 2227-9040 |
| Appears in Collections: | Articles publicats en revistes (Enginyeria Química i Química Analítica) |
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| 673372.pdf | 818.66 kB | Adobe PDF | View/Open |
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