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Title: | The evolution of CT diagnosed papillae tip microcalcifications: can we predict the development of stones? |
Author: | Ciudin, Alexandru Luque Gálvez, Ma. Pilar Salvador, Rafael Diaconu, Mihai Gabriel Franco de Castro, Agustín Collado Belvis, Antonio Sánchez, Javier Constantin, Vlad Alvarez Vijande, Ricardo Nicolau, Carlos Alcaraz Asensio, Antonio |
Keywords: | Càlculs renals Malalties de l'aparell genitourinari Anamnesi Tomografia computada per emissió de fotó simple Estudi de casos Kidney calculi Genitourinary organs diseases Medical history taking Single-photon emission computed tomography Case studies |
Issue Date: | 3-Jun-2014 |
Publisher: | Mary Ann Liebert |
Abstract: | OBJECTIVES: To determine the incidence of computed tomography (CT) identifiable Randall plaques in a CT explored population; to determine the clinical relevance of this radiological finding by a 7-year follow-up; to determine a cut point to identify a population with high risk of developing calcium stone disease (SD). MATERIALS AND METHODS: Retrospective study of all patients explored by abdominal CT in our center between January and March 2005. INCLUSION CRITERIA: age 30-60 years and no SD. Papillae attenuation was measured on nonenhanced CT in Hounsfield units (HU) and the mean of all papillae was calculated. Patients were re-evaluated after 7 years to identify calcium stone formers. Anamnesis and already available CT, ultrasound, kidney, ureter, and bladder radiograph (KUB) or intravenous urography (IVU) images performed as part of their follow-up were used. In patients with no follow-up, ultrasound and KUB were to be performed. Pearson correlation, Student t-test, and the receiver operator curve were used for statistical analysis. RESULTS: A total of 362 patients fulfilled the inclusion criteria and were analyzed; 12 developed calcium SD after 7 years. A significant difference was encountered between the papillae attenuation of stone formers (SF) versus non-SF (47.2HU vs. 35.5HU, p=0.001). There was good correlation between papillae attenuation and the possibility of developing SD (R=0.87). An optimal cut point of 43HU with a sensitivity of 81% and specificity of 97%, area under the curve 0.91, separated SF and non-SF. CONCLUSION: Patients with high papillae density have a higher risk of developing SD. A cut point of 43HU could accurately be used to identify a high-risk population. |
Note: | Reproducció del document publicat a: https://doi.org/10.1089/end.2014.0151 |
It is part of: | Journal of Endourology and Part B, Videourology, 2014, vol. 28, num. 8, p. 1016-1021 |
URI: | http://hdl.handle.net/2445/117089 |
Related resource: | https://doi.org/10.1089/end.2014.0151 |
ISSN: | 0892-7790 |
Appears in Collections: | Articles publicats en revistes (Cirurgia i Especialitats Medicoquirúrgiques) |
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