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Title: Authentication of gold nanoparticle encoded pharmaceutical tablets using polarimetric signatures
Author: Carnicer González, Arturo
Arteaga Barriel, Oriol
Suñé i Negre, Josep M. (Josep Maria)
Javidi, Bahram
Keywords: Comprimits (Medicina)
Reconeixement òptic de formes
Tablets (Medicine)
Optical pattern recognition
Issue Date: 26-Sep-2016
Publisher: Optical Society of America
Abstract: The counterfeiting of pharmaceutical products represents concerns for both industry and the safety of the general public. Falsification produces losses to companies and poses health risks for patients. In order to detect fake pharmaceutical tablets, we propose producing film-coated tablets with gold nanoparticle encoding. These coated tablets contain unique polarimetric signatures. We present experiments to show that ellipsometric optical techniques, in combination with machine learning algorithms, can be used to distinguish genuine and fake samples. To the best of our knowledge, this is the first report using gold nanoparticles encoded with optical polarimetric classifiers to prevent the counterfeiting of pharmaceutical products.
Note: Versió postprint del document publicat a:
It is part of: Optics Letters, 2016, vol. 41, num. 19, p. 4507-4510
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ISSN: 0146-9592
Appears in Collections:Articles publicats en revistes (Física Aplicada)
Articles publicats en revistes (Farmàcia, Tecnologia Farmacèutica i Fisicoquímica)

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