Please use this identifier to cite or link to this item:
Title: Short-term exposure to traffic-related air pollution and ischemic stroke onset in Barcelona, Spain
Author: Vivanco Hidalgo, Rosa Maria
Wellenius, Gregory A.
Basagaña, Xavier
Cirach, Marta
Gonzalez, Alejandra Gómez
Ceballos, Pablo de
Zabalza, Ana
Jiménez Conde, Jordi
Soriano Tarraga, Carolina
Giralt Steinhauer, Eva
Alastuey, Andrés
Querol Carceller, Xavier
Sunyer Deu, Jordi
Roquer, Jaume
Keywords: Contaminació atmosfèrica
Atmospheric pollution
Issue Date: Apr-2018
Publisher: Elsevier
Abstract: OBJECTIVE: To assess the relationship between short-term exposure to outdoor ambient air pollutants (fine particulate matter [PM2.5] and black carbon [BC]), ischemic stroke (IS) and its different subtypes, and the potential modifying effect of neighborhood greenspace and noise. METHODS: This time-stratified case-crossover study was based on IS and transient ischemic attacks (TIA) recorded in a hospital-based prospective stroke register (BASICMAR 2005-2014) in Barcelona (Catalonia, Spain). Daily and hourly pollutant concentrations and meteorological data were obtained from monitoring stations in the city. Time-lags (from previous 72h to acute stroke onset) were analyzed. Greenness and noise were determined from the Normalized Difference Vegetation Index (NDVI) and daily average noise level at the street nearest to residential address, respectively. RESULTS: The 2742 cases with known onset date and time, living in the study area, were analyzed. After adjusting for temperature, no statistically significant association between pollutants exposure and overall stroke risk was found. In subtype analysis, an association was detected between BC exposure at 24-47h (odds ratio, 1.251; 95% confidence interval [CI], 1.001-1.552; P = 0.042) and 48-72h (1.211; 95% CI, 0.988-1.484; P = 0.065) time-lag prior to stroke onset and large-artery atherosclerosis subtype. No clear modifying effect of greenness or noise was observed. CONCLUSIONS: Overall, no association was found between PM2.5 and BC exposure and acute IS risk. By stroke subtype, large-artery atherosclerotic stroke could be triggered by daily increases in BC, a diesel fuel-related pollutant in the study area.
Note: Reproducció del document publicat a:
It is part of: Environmental Research, 2018, vol. 162, p. 160-165
Related resource:
ISSN: 0013-9351
Appears in Collections:Articles publicats en revistes (ISGlobal)

Files in This Item:
File Description SizeFormat 
vivanco-hidalgo2018_2872.pdf332.99 kBAdobe PDFView/Open

This item is licensed under a Creative Commons License Creative Commons