Please use this identifier to cite or link to this item:
http://hdl.handle.net/2445/122431
Title: | Detection of heteromers formed by cannabinoid CB1, dopamine D2, and adenosine A2A G-protein-coupled receptors by combining bimolecular fluorescence complementation and bioluminescence energy transfer |
Author: | Navarro Brugal, Gemma Carriba Domínguez, Paulina Gandía, Jorge Ciruela Alférez, Francisco Casadó, Vicent Cortés Tejedor, Antonio Mallol Montero, Josefa Canela Campos, Enric I. Lluís i Biset, Carme Franco Fernández, Rafael |
Keywords: | Adenosina Proteïnes Receptors cel·lulars Adenosine Proteins Cell receptors |
Issue Date: | 11-Oct-2008 |
Publisher: | Hindawi |
Abstract: | Functional interactions in signaling occur between dopamine D2 (D2R) and cannabinoid CB1 (CB1R) receptors, between CB1R and adenosine A2A (A2AR) receptors, and between D2R and A2AR. Furthermore, direct molecular interactions have been reported for the pairs CB1R-D2R, A2AR-D2R, and CB1R-A2AR. Here a combination of bimolecular fluorescence complementation and bioluminescence energy transfer techniques was used to identify the occurrence of D2R-CB1R-A2AR hetero-oligomers in living cells. |
Note: | Reproducció del document publicat a: https://doi.org/10.1100/tsw.2008.136 |
It is part of: | Scientific World Journal, 2008, vol. 8, p. 1088-1097 |
URI: | http://hdl.handle.net/2445/122431 |
Related resource: | https://doi.org/10.1100/tsw.2008.136 |
ISSN: | 1537-744X |
Appears in Collections: | Articles publicats en revistes (Bioquímica i Biomedicina Molecular) Articles publicats en revistes (Bioquímica i Fisiologia) Articles publicats en revistes (Patologia i Terapèutica Experimental) Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer) |
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