Title: | Molecular Mechanisms Of Cell Death: Recommendations Of The Nomenclature Committee On Cell Death 2018 |
Author: | Galluzzi, Lorenzo Vitale, Ilio Aaronson, Stuart A. Abrams, John M. Adam, Dieter Agostinis, Patrizia Alnemri, Emad S. Altucci, Lucia Amelio, Ivano Andrews, David W. Annicchiarico-Petruzzelli, Margherita Cecconi, Francesco Cidlowski, John A. Chan, Francis K. M. Chandel, Navdeep S. Cheng, Emily H. Hengartner, Michael O. Czabotar, Peter E. Angiolella, Vincenzo D' Dawson, Ted M. Dawson, Valina L. Madeo, Frank Marine, Jean-Christophe Fimia, Gian Maria Knight, Richard A. De Laurenzi, Vincenzo Maria, Ruggero de Debatin, Klaus-Michael DeBerardinis, Ralph J. Hetz, Claudio Deshmukh, Mohanish Daniele, Nicola di Martin, Seamus J. Virgilio, Francesco di Dixit, Vishva M. Dixon, Scott J. Kumar, Sharad Fulda, Simone García-Sáez, Ana J. Garg, Abhishek D. Garrido, Carmen Penninger, Josef M. Medema, Jan Paul Malewicz, Michal Gavathiotis, Evripidis Golstein, Pierre Martinou, Jean-Claude Gottlieb, Eyal Lee, Sam W. Green, Douglas R. Greene, Lloyd A. Gronemeyer, Hinrich Gross, Atan Hajnoczky, Gyorgy Malorni, Walter Ichijo, Hidenori Jaattela, Marja Joseph, Bertrand Jost, Philipp J. Shao, Feng Pervaiz, Shazib Juin, Philippe P. Kaiser, William J. Pereira, David M. Karin, Michael Manic, Gwenola Kaufmann, Thomas Kepp, Oliver Kimchi, Adi Mehlen, Patrick Kitsis, Richard N. Lemasters, John J. Levine, Beth Linkermann, Andreas Lipton, Stuart A. Vandenabeele, Peter Silke, John Lockshin, Richard A. Meier, Pascal Shi, Yufang López Otin, Carlos Lowe, Scott W. Luedde, Tom Lugli, Enrico Peter, Marcus E. MacFarlane, Marion Melino, Sonia Miao, Edward A. Molkentin, Jeffery D. Moll, Ute M. Zhivotovsky, Boris Antonov, Alexey V. Piacentini, Mauro Vander Heiden, Matthew G. Muñoz Pinedo, Cristina Nagata, Shigekazu Nuñez, Gabriel Oberst, Andrew Simon, Hans-Uwe Oren, Moshe Overholtzer, Michael Arama, Eli Pagano, Michele Panaretakis, Theocharis Pasparakis, Manolis Villunger, Andreas Pinton, Paolo Prehn, Jochen H. M. Puthalakath, Hamsa Rabinovich, Gabriel A. Chipuk, Jerry E. Barlev, Nickolai A. Zitvogel, Laurence Rehm, Markus Rizzuto, Rosario Baehrecke, Eric H. Rodrigues, Cecilia M. P. Virgin, Herbert W. Rubinsztein, David C. Rudel, Thomas Ryan, Kevin M. Sayan, Emre Scorrano, Luca Melino, Gerry Sistigu, Antonella Stockwell, Brent R. Strasser, Andreas Szabadkai, Gyorgy Duckett, Colin S. Cohen, Gerald M. Tait, Stephen W. G. Tang, Daolin Ciechanover, Aaron Tavernarakis, Nektarios Kroemer, Guido Thorburn, Andrew Tsujimoto, Yoshihide Turk, Boris Bazan, Nicolas G. Vanden Berghe, Tom Vousden, Karen H. Vucic, Domagoj Wagner, Erwin F. Walczak, Henning Hardwick, J. Marie El-Deiry, Wafik S. Wallach, David Bernassola, Francesca Dynlacht, Brian D. Wang, Ying Wells, James A. Wood, Will Yuan, Junying Conrad, Marcus Zakeri, Zahra Bertrand, Mathieu J. M. Bianchi, Katiuscia Blagosklonny, Mikhail V. Blomgren, Klas Klionsky, Daniel J. Borner, Christoph Cubillos-Ruiz, Juan R. Harris, Isaac S. Boya, Patricia Brenner, Catherine Campanella, Michelangelo Candi, Eleonora Elrod, John W. Carmona-Gutierrez, Didac |
Keywords: | Mort cel·lular Nomenclatura Cell death Nomenclature |
Issue Date: | 1-Mar-2018 |
Publisher: | Nature Publishing Group |
Abstract: | Over the past decade, the Nomenclature Committee on Cell Death (NCCD) has formulated guidelines for the definition and interpretation of cell death from morphological, biochemical, and functional perspectives. Since the field continues to expand and novel mechanisms that orchestrate multiple cell death pathways are unveiled, we propose an updated classification of cell death subroutines focusing on mechanistic and essential (as opposed to correlative and dispensable) aspects of the process. As we provide molecularly oriented definitions of terms including intrinsic apoptosis, extrinsic apoptosis, mitochondrial permeability transition (MPT)-driven necrosis, necroptosis, ferroptosis, pyroptosis, parthanatos, entotic cell death, NETotic cell death, lysosome-dependent cell death, autophagy-dependent cell death, immunogenic cell death, cellular senescence, and mitotic catastrophe, we discuss the utility of neologisms that refer to highly specialized instances of these processes. The mission of the NCCD is to provide a widely accepted nomenclature on cell death in support of the continued development of the field. |
Note: | Reproducció del document publicat a: https://doi.org/10.1038/s41418-017-0012-4 |
It is part of: | Cell Death And Differentiation, 2018, Vol. 25, Issue 3, P. 486-541 |
URI: | http://hdl.handle.net/2445/123994 |
Related resource: | https://doi.org/10.1038/s41418-017-0012-4 |
Appears in Collections: | Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))
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