1. Dipòsit Digital de la Universitat de Barcelona
  2. Recerca
  3. Ciències Clíniques
  4. Articles publicats en revistes (Ciències Clíniques)
Please use this identifier to cite or link to this item: http://hdl.handle.net/2445/124064
Full metadata record
DC FieldValueLanguage
dc.contributor.authorFredrick R. Schumacher-
dc.contributor.authorSchmit, Stephanie L.-
dc.contributor.authorJiao, Shuo-
dc.contributor.authorEdlund, Christopher K.-
dc.contributor.authorWang, Hansong-
dc.contributor.authorZhang, Ben-
dc.contributor.authorHsu, Li-
dc.contributor.authorHuang, Shu-Chen-
dc.contributor.authorFischer, Christopher P.-
dc.contributor.authorHarju, John F.-
dc.contributor.authorIdos, Gregory E.-
dc.contributor.authorLejbkowicz, Flavio-
dc.contributor.authorManion, Frank J.-
dc.contributor.authorMcDonnell, Kevin-
dc.contributor.authorMcNeil, Caroline E.-
dc.contributor.authorMelas, Marilena-
dc.contributor.authorRennert, Hedy S.-
dc.contributor.authorShi, Wei-
dc.contributor.authorThomas, Duncan C.-
dc.contributor.authorBerg, David J. Van den-
dc.contributor.authorHutter, Carolyn M.-
dc.contributor.authorAragaki, Aaron K.-
dc.contributor.authorButterbach, Katja-
dc.contributor.authorCaan, Bette J.-
dc.contributor.authorCarlson, Christopher S.-
dc.contributor.authorChanock, Stephen J.-
dc.contributor.authorCurtis, Keith R.-
dc.contributor.authorFuchs, Charles S.-
dc.contributor.authorGala, Manish-
dc.contributor.authorGiovannucci, Edward L.-
dc.contributor.authorGogarten, Stephanie M.-
dc.contributor.authorHayes, Richard B.-
dc.contributor.authorHenderson, Brian E.-
dc.contributor.authorHunter, David J.-
dc.contributor.authorJackson, Rebecca D. J.-
dc.contributor.authorKolonel, Laurence N.-
dc.contributor.authorKooperberg, Charles-
dc.contributor.authorKüry, Sébastien-
dc.contributor.authorLaCroix, Andrea-
dc.contributor.authorMoreno Aguado, Víctor-
dc.date.accessioned2018-08-01T08:58:29Z-
dc.date.available2018-08-01T08:58:29Z-
dc.date.issued2015-07-07-
dc.identifier.issn2041-1723-
dc.identifier.urihttp://hdl.handle.net/2445/124064-
dc.descriptionEl document inclou una pàgina final amb una correcció (corrigendum). Aquesta, per si sola, té el següent DOI: 10.1038/ncomms9739 i es va publicar al mateix vol. 6.-
dc.description.abstractGenetic susceptibility to colorectal cancer is caused by rare pathogenic mutations and common genetic variants that contribute to familial risk. Here we report the results of a two-stage association study with 18,299 cases of colorectal cancer and 19,656 controls, with follow-up of the most statistically significant genetic loci in 4,725 cases and 9,969 controls from two Asian consortia. We describe six new susceptibility loci reaching a genome-wide threshold of P<5.0E-08. These findings provide additional insight into the underlying biological mechanisms of colorectal cancer and demonstrate the scientific value of large consortia-based genetic epidemiology studies.-
dc.format.extent6 p.-
dc.format.mimetypeapplication/pdf-
dc.language.isoeng-
dc.publisherNature Publishing Group-
dc.relation.isformatofReproducció del document publicat a: https://doi.org/10.1038/ncomms8138-
dc.relation.ispartofNature Communications, 2015, vol. 6, num. 7138, p. 1-6-
dc.relation.urihttps://doi.org/10.1038/ncomms8138-
dc.rightscc-by (c) Fredrick R. Schumacher et al., 2015-
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/es-
dc.sourceArticles publicats en revistes (Ciències Clíniques)-
dc.subject.classificationCàncer colorectal-
dc.subject.classificationGenoma humà-
dc.subject.classificationGenètica-
dc.subject.otherColorectal cancer-
dc.subject.otherHuman genome-
dc.subject.otherGenetics-
dc.titleGenome-wide association study of colorectal cancer identifies six new susceptibility loci-
dc.typeinfo:eu-repo/semantics/article-
dc.typeinfo:eu-repo/semantics/publishedVersion-
dc.identifier.idgrec660449-
dc.date.updated2018-08-01T08:58:29Z-
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess-
dc.identifier.pmid26151821-
Appears in Collections:Articles publicats en revistes (Ciències Clíniques)
Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))

Files in This Item:
File Description SizeFormat 
660449.pdf584.04 kBAdobe PDFView/Open
Show simple item record


This item is licensed under a Creative Commons License Creative Commons