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http://hdl.handle.net/2445/124688
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DC Field | Value | Language |
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dc.contributor.author | Palacín, Arantxa | - |
dc.contributor.author | Gómez Casado, Cristina | - |
dc.contributor.author | Rivas, Luis A. | - |
dc.contributor.author | Aguirre, Jacobo | - |
dc.contributor.author | Tordesillas, Leticia | - |
dc.contributor.author | Bartra Tomàs, Joan | - |
dc.contributor.author | Blanco, Carlos | - |
dc.contributor.author | Carrillo, Teresa | - |
dc.contributor.author | Cuesta Herranz, Javier | - |
dc.contributor.author | Frutos, Consolación de | - |
dc.contributor.author | García Álvarez-Eire, Genoveva | - |
dc.contributor.author | Fernández, Francisco J. | - |
dc.contributor.author | Gamboa, Pedro | - |
dc.contributor.author | Muñoz, Rosa | - |
dc.contributor.author | Sánchez-Monge, Rosa | - |
dc.contributor.author | Sirvent, Sofía | - |
dc.contributor.author | Torres, María J. | - |
dc.contributor.author | Varela Losada, Susana | - |
dc.contributor.author | Rodríguez, Rosalía | - |
dc.contributor.author | Parro, Victor | - |
dc.contributor.author | Blanca, Miguel | - |
dc.contributor.author | Salcedo, Gabriel | - |
dc.contributor.author | Díaz Perales, Araceli | - |
dc.date.accessioned | 2018-09-19T16:47:30Z | - |
dc.date.available | 2018-09-19T16:47:30Z | - |
dc.date.issued | 2012-12-14 | - |
dc.identifier.issn | 1932-6203 | - |
dc.identifier.uri | http://hdl.handle.net/2445/124688 | - |
dc.description.abstract | The study of cross-reactivity in allergy is key to both understanding. the allergic response of many patients and providing them with a rational treatment In the present study, protein microarrays and a co-sensitization graph approach were used in conjunction with an allergen microarray immunoassay. This enabled us to include a wide number of proteins and a large number of patients, and to study sensitization profiles among members of the LTP family. Fourteen LTPs from the most frequent plant food-induced allergies in the geographical area studied were printed into a microarray specifically designed for this research. 212 patients with fruit allergy and 117 food-tolerant pollen allergic subjects were recruited from seven regions of Spain with different pollen profiles, and their sera were tested with allergen microarray. This approach has proven itself to be a good tool to study cross-reactivity between members of LTP family, and could become a useful strategy to analyze other families of allergens. | - |
dc.format.extent | 10 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Public Library of Science (PLoS) | - |
dc.relation.isformatof | Reproducció del document publicat a: https://doi.org/10.1371/journal.pone.0050799 | - |
dc.relation.ispartof | PLoS One, 2012, vol. 7, num. 12, p. e50799 | - |
dc.relation.uri | https://doi.org/10.1371/journal.pone.0050799 | - |
dc.rights | cc-by (c) Palacín, Arantxa et al., 2012 | - |
dc.rights.uri | http://creativecommons.org/licenses/by/3.0/es | - |
dc.source | Articles publicats en revistes (Medicina) | - |
dc.subject.classification | Al·lèrgens | - |
dc.subject.classification | Proteïnes vegetals | - |
dc.subject.classification | Immunologia | - |
dc.subject.other | Allergens | - |
dc.subject.other | Plant proteins | - |
dc.subject.other | Immunology | - |
dc.title | Graph based study of allergen cross-reactivity of plant lipid transfer proteins (LTPs) using microarray in a multicenter study. | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.identifier.idgrec | 636429 | - |
dc.date.updated | 2018-09-19T16:47:31Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 23272072 | - |
Appears in Collections: | Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer) Articles publicats en revistes (Medicina) |
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636429.pdf | 966.59 kB | Adobe PDF | View/Open |
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