Title: | Iarc Monographs: 40 Years Of Evaluating Carcinogenic Hazards To Humans |
Author: | Pearce, Neil Blair, Aaron Vineis, Paolo Ahrens, Wolfgang Andersen, Aage Antó i Boqué, Josep Maria Armstrong, Bruce K. Baccarelli, Andrea A. Beland, Frederick A. Berrington, Amy Bertazzi, Pier Alberto Forastiere, Francesco Hemon, Denis Frentzel-Beyme, Rainer Fritschi, Lin Kjuus, Helge Gerin, Michel Goldberg, Marcel Grandjean, Philippe Grimsrud, Tom K. Haines, Andy Kriebel, David Hartge, Patricia Hertz-Picciotto, Irva Hansen, Johnni Hauptmann, Michael Heederik, Dick J. J. Hemminki, Kari Hoppin, Jane A. Lynch, Charles F. Huff, James Kogevinas, Manolis Merchant, James A. Jarvholm, Bengt Kang, Daehee Karagas, Margaret R. Kjaerheim, Kristina Kristensen, Petter Kromhout, Hans Parent, Marie‑Elise Laden, Francine Lebailly, Pierre Lemasters, Grace Lubin, Jay H. Lynge, Elsebeth Perry, Melissa J. Mannetje, Andrea 't Merler, Enzo McMichael, Anthony J. McLaughlin, John R. Marrett, Loraine Martuzzi, Marco Merletti, Franco Ritter, Leonard Miller, Anthony B. Perera, Federica P. Sandler, Dale P. Mirer, Franklin E. Monson, Richard Nordby, Karl-Cristian Olshan, Andrew F. Pesatori, Angela Cecilia Pirastu, Roberta Simonato, Lorenzo Porta, Miquel, 1957- Pukkala, Eero Rice, Carol Richardson, David B. Ritz, Beate Smith, Martyn T. Ronckers, Cecile M. Sanjosé Llongueras, Silvia de Rushton, Lesley Rusiecki, Jennifer A. Rusyn, Ivan Samet, Jonathan M. Schernhammer, Eva Stewart, Bernard W. Seniori Costantini, Adele Smith, Allan H. Vermeulen, Roel C. H. Seixas, Noah Shy, Carl Siemiatycki, Jack Silverman, Debra T. Spinelli, John J. Spitz, Margaret R. Birnbaum, Linda S. Stallones, Lorann Stayner, Leslie T. Steenland, Kyle Stenzel, Mark Stewart, Patricia A. Bucher, John R. Symanski, Elaine Victora, Cesar G. Terracini, Benedetto Tolbert, Paige E. Vainio, Harri Vena, John Ward, Elizabeth M. Comba, Pietro Weinberg, Clarice R. Brownson, Ross C. Fletcher, Tony Weisenburger, Dennis D. Wesseling, Catharina Weiderpass, Elisabete Hoar Zahm, Shelia Cantor, Kenneth P. Cardis, Elisabeth Demers, Paul A. Cherrie, John W. Christiani, David C. Cocco, Pierluigi Coggon, David Dement, John M. Gustavsson, Per Douwes, Jeroen Fontham, Elizabeth Eisen, Ellen A. Engel, Lawrence S. Fenske, Richard A. Fleming, Lora E. |
Keywords: | Càncer Cancer |
Issue Date: | 1-Jun-2015 |
Publisher: | National Institute of Environmental Health Sciences |
Abstract: | BACKGROUND: Recently, the International Agency for Research on Cancer (IARC) Programme for the Evaluation of Carcinogenic Risks to Humans has been criticized for several of its evaluations, and also for the approach used to perform these evaluations. Some critics have claimed that failures of IARC Working Groups to recognize study weaknesses and biases of Working Group members have led to inappropriate classification of a number of agents as carcinogenic to humans. OBJECTIVES: The authors of this Commentary are scientists from various disciplines relevant to the identification and hazard evaluation of human carcinogens. We examined criticisms of the IARC classification process to determine the validity of these concerns. Here, we present the results of that examination, review the history of IARC evaluations, and describe how the IARC evaluations are performed. DISCUSSION: We concluded that these recent criticisms are unconvincing. The procedures employed by IARC to assemble Working Groups of scientists from the various disciplines and the techniques followed to review the literature and perform hazard assessment of various agents provide a balanced evaluation and an appropriate indication of the weight of the evidence. Some disagreement by individual scientists to some evaluations is not evidence of process failure. The review process has been modified over time and will undoubtedly be altered in the future to improve the process. Any process can in theory be improved, and we would support continued review and improvement of the IARC processes. This does not mean, however, that the current procedures are flawed. CONCLUSIONS: The IARC Monographs have made, and continue to make, major contributions to the scientific underpinning for societal actions to improve the public's health. |
Note: | Reproducció del document publicat a: https://doi.org/10.1289/ehp.1409149 |
It is part of: | Environmental Health Perspectives, 2015, vol. 123, num. 6, p. 507-514 |
URI: | http://hdl.handle.net/2445/125713 |
Related resource: | https://doi.org/10.1289/ehp.1409149 |
Appears in Collections: | Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))
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