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http://hdl.handle.net/2445/126014
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DC Field | Value | Language |
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dc.contributor.author | Pinazo Durán, María Dolores | - |
dc.contributor.author | Gómez Ulla, Francisco | - |
dc.contributor.author | Arias Barquet, Lluís | - |
dc.contributor.author | Araiz, Javier | - |
dc.contributor.author | Casaroli Marano, Ricardo Pedro | - |
dc.contributor.author | Gallego Pinazo, Roberto | - |
dc.contributor.author | García Medina, Jose J. | - |
dc.contributor.author | López Gálvez, María Isabel | - |
dc.contributor.author | Manzanas, Lucía | - |
dc.contributor.author | Salas, Anna | - |
dc.contributor.author | Zapata, Miguel | - |
dc.contributor.author | Díaz Llopis, Manuel | - |
dc.contributor.author | García Layana, Alfredo | - |
dc.date.accessioned | 2018-11-12T11:39:56Z | - |
dc.date.available | 2018-11-12T11:39:56Z | - |
dc.date.issued | 2014-01-23 | - |
dc.identifier.issn | 2090-004X | - |
dc.identifier.uri | http://hdl.handle.net/2445/126014 | - |
dc.description.abstract | Purpose. To review the proposed pathogenic mechanisms of age macular degeneration (AMD), as well as the role of antioxidants (AOX) and omega-3 fatty acids (omega-3) supplements in AMD prevention. Materials and Methods. Current knowledge on the cellular/molecular mechanisms of AMD and the epidemiologic/experimental studies on the effects of AOX and omega-3 were addressed all together with the scientific evidence and the personal opinion of professionals involved in the Retina Group of the OFTARED (Spain). Results. High dietary intakes of omega-3 and macular pigments lutein/zeaxanthin are associated with lower risk of prevalence and incidence in AMD. The Age-Related Eye Disease study (AREDS) showed a beneficial effect of high doses of vitamins C, E, beta-carotene, and zinc/copper in reducing the rate of progression to advanced AMD in patients with intermediate AMD or with one-sided late AMD. The AREDS-2 study has shown that lutein and zeaxanthin may substitute beta-carotene because of its potential relationship with increased lung cancer incidence. Conclusion. Research has proved that elder people with poor diets, especially with low AOX and omega-3 micronutrients intake and subsequently having low plasmatic levels, are more prone to developing AMD. Micronutrient supplementation enhances antioxidant defense and healthy eyes and might prevent/retard/modify AMD. | - |
dc.format.extent | 15 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Hindawi | - |
dc.relation.isformatof | Reproducció del document publicat a: https://doi.org/10.1155/2014/901686 | - |
dc.relation.ispartof | Journal of Ophthalmology, 2014, vol. 2014 | - |
dc.relation.uri | https://doi.org/10.1155/2014/901686 | - |
dc.rights | cc-by (c) Pinazo Durán, Maria D. et al., 2014 | - |
dc.rights.uri | http://creativecommons.org/licenses/by/3.0/es | - |
dc.source | Articles publicats en revistes (Cirurgia i Especialitats Medicoquirúrgiques) | - |
dc.subject.classification | Malalties de la retina | - |
dc.subject.classification | Suplements nutritius | - |
dc.subject.other | Retinal diseases | - |
dc.subject.other | Dietary supplements | - |
dc.title | Do nutritional supplements have a role in age macular degeneration prevention? | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.identifier.idgrec | 637826 | - |
dc.date.updated | 2018-11-12T11:39:57Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 24672708 | - |
Appears in Collections: | Articles publicats en revistes (Ciències Clíniques) Articles publicats en revistes (Cirurgia i Especialitats Medicoquirúrgiques) Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
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637826.pdf | 954.58 kB | Adobe PDF | View/Open |
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