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http://hdl.handle.net/2445/126417
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DC Field | Value | Language |
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dc.contributor.author | Sanjosé Llongueras, Silvia de | - |
dc.contributor.author | Benavente, Yolanda | - |
dc.contributor.author | Vajdic, Claire M. | - |
dc.contributor.author | Engels, Eric A. | - |
dc.contributor.author | Morton, Lindsay M. | - |
dc.contributor.author | Bracci, Paige M. | - |
dc.contributor.author | Spinelli, John J. | - |
dc.contributor.author | Zheng, Tongzhang | - |
dc.contributor.author | Zhang, Yawei | - |
dc.contributor.author | Franceschi, Silvia | - |
dc.contributor.author | Talamini, Renato | - |
dc.contributor.author | Holly, Elizabeth A. | - |
dc.contributor.author | Grulich, Andrew E. | - |
dc.contributor.author | Cerhan, James R. | - |
dc.contributor.author | Hartge, Patricia | - |
dc.contributor.author | Cozen, Wendy | - |
dc.contributor.author | Boffetta, Paolo | - |
dc.contributor.author | Brennan, Paul | - |
dc.contributor.author | Maynadié, Marc | - |
dc.contributor.author | Cocco, Pierluigi | - |
dc.contributor.author | Bosch, Ramon | - |
dc.contributor.author | Foretova, Lenka | - |
dc.contributor.author | Staines, Anthony | - |
dc.contributor.author | Becker, Nikolaus | - |
dc.contributor.author | Nieters, Alexandra | - |
dc.date.accessioned | 2018-11-23T14:23:26Z | - |
dc.date.available | 2018-11-23T14:23:26Z | - |
dc.date.issued | 2008-04 | - |
dc.identifier.uri | http://hdl.handle.net/2445/126417 | - |
dc.description.abstract | Background & Aims: increasing evidence points towards a role of hepatitis C virus (HCV) infection in causing malignant lymphomas. We pooled case-control study data to provide robust estimates of the risk of non-Hodgkin's lymphoma (NHL) subtypes after HCV infection. Methods: The analysis included 7 member studies from the International Lymphoma Epidemiology Consortium (InterLymph) based in Europe, North America, and Australia. Adult cases of NHL (n = 4784) were diagnosed between 1988 and 2004 and controls (n = 6269) were matched by age, sex, and study center. All studies used third-generation enzyme-linked immunosorbent assays to test for antibodies against HCV in serum samples. Participants who were human immunodeficiency virus positive or were organ-transplant recipients were excluded. Results: HCV infection was detected in 172 NHL cases (3.60%) and in 169 (2.70%) controls (odds ratio [OR], 1.78; 95% confidence interval [CI], 1.40 -2.25). In subtype-specific analyses, HCV prevalence was associated with marginal zone lymphoma (OR, 2.47; 95% CI, 1.44-4.23), diffuse large B-cell lymphoma (OR, 2.24; 95% CI, 1.682.99), and lymphoplasmacytic lymphoma (OR, 2.57; 95% CI, 1.14-5.79). Notably, risk estimates were not increased for follicular lymphoma (OR, 1.02; 95% CI, 0.65-1.60). Conclusions: These results confirm the association between HCV infection and NHL and specific B-NHL subtypes (diffuse large B-cell lymphoma, marginal zone lymphoma, and lymphoplasmacytic lymphoma). | - |
dc.format.extent | 15 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Elsevier Science | - |
dc.relation.isformatof | Versió postprint del document publicat a: https://doi.org/10.1016/j.cgh.2008.02.011 | - |
dc.relation.ispartof | Clinical Gastroenterology and Hepatology, 2008, vol. 6, num. 4, p. 451-458 | - |
dc.relation.uri | https://doi.org/10.1016/j.cgh.2008.02.011 | - |
dc.rights | (c) AGA Institute, 2008 | - |
dc.source | Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) | - |
dc.subject.classification | Hepatitis C | - |
dc.subject.classification | Malaltia de Hodgkin | - |
dc.subject.other | Hodgkin's disease | - |
dc.title | Hepatitis C and Non-Hodgkin Lymphoma Among 4784 Cases and 6269 Controls From the International Lymphoma Epidemiology Consortium | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/acceptedVersion | - |
dc.date.updated | 2018-07-25T10:41:33Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 18387498 | - |
Appears in Collections: | Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
Files in This Item:
File | Description | Size | Format | |
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De SanjoseS.pdf | 1.15 MB | Adobe PDF | View/Open |
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