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DC Field | Value | Language |
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dc.contributor.author | Taylor, Sylvia | - |
dc.contributor.author | Bunge, Eveline | - |
dc.contributor.author | Bakker, Marina | - |
dc.contributor.author | Castellsagué, Xavier | - |
dc.date.accessioned | 2018-12-10T12:48:58Z | - |
dc.date.available | 2018-12-10T12:48:58Z | - |
dc.date.issued | 2016-06-14 | - |
dc.identifier.uri | http://hdl.handle.net/2445/126840 | - |
dc.description.abstract | Background: Human papillomavirus (HPV) vaccines were designed to prevent cervical cancer in women and their provision remains a major public health need. However, HPV is also a major cause of non-cervical anogenital and oropharyngeal cancers and the potential benefit of vaccination likely extends beyond cervical cancer. Methods: A systematic literature search of PubMed (1995-2014) identified publications assessing the incidence, persistence, and clearance of non-cervical anogenital/oral HPV infections. Comparability with cervical HPV was assessed by identifying articles assessing the same or similar populations. Results: Available data suggest high incidence rates of non-cervical HPV infection in men and women, with HPV-16 predominating in all sites. The incidence of high risk HPV per 100 person-years ranged from 11.4 to 72.9 for penile infections, 6.7-47.9 at other male genital sites, and 4.4-36.7 and 5.3-23.4 for anal infections in men and women, respectively. The incidence per 100 person-years of oral infection with any HPV type ranged from 5.7 to 6.7 in men and 6.8-39.6 in women. Within the limitations of the data, there was a general pattern of higher incidence and clearance of non-cervical genital HPV infections, compared to cervical infections. HIV status, circumcision, number of sex partners and partner HPV status significantly influenced high-risk HPV incidence/clearance at male anogenital sites. Few studies assessed risk factors for oral HPV. Conclusions: Parallels appear to exist between the epidemiology of cervical and non-cervical HPV infections in terms of incidence, HPV-type distribution, and risk factors for infection. Available data suggest that non-cervical genital HPV infections may occur more frequently, with higher clearance rates, than cervical infections. More extensive studies could provide useful information for estimating vaccine impact, the wider cost-benefit of HPV vaccination, and guiding vaccination policy. | - |
dc.format.extent | 21 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | BioMed Central | - |
dc.relation.isformatof | Reproducció del document publicat a: https://doi.org/10.1186/s12879-016-1633-9 | - |
dc.relation.ispartof | BMC Infectious Diseases, 2016, vol. 16, num. 293 | - |
dc.relation.uri | https://doi.org/10.1186/s12879-016-1633-9 | - |
dc.rights | cc by (c) Taylor et al., 2016 | - |
dc.rights.uri | http://creativecommons.org/licenses/by/3.0/es/ | * |
dc.source | Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) | - |
dc.subject.classification | Vacuna del papil·lomavirus | - |
dc.subject.classification | Càncer de coll uterí | - |
dc.subject.other | Papillomavirus vaccines | - |
dc.subject.other | Cervix cancer | - |
dc.title | The incidence, clearance and persistence of non-cervical human papillomavirus infections: a systematic review of the literature | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.date.updated | 2018-07-25T07:48:05Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 27301867 | - |
Appears in Collections: | Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
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TaylorS.pdf | 1.01 MB | Adobe PDF | View/Open |
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