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http://hdl.handle.net/2445/127057
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DC Field | Value | Language |
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dc.contributor.author | Formiga Pérez, Francesc | - |
dc.contributor.author | Ferrer, Assumpta | - |
dc.contributor.author | Padros, Gloria | - |
dc.contributor.author | Montero Saez, Abelardo | - |
dc.contributor.author | Giménez Argente, Carme | - |
dc.contributor.author | Corbella, Xavier | - |
dc.date.accessioned | 2018-12-19T12:30:48Z | - |
dc.date.available | 2018-12-19T12:30:48Z | - |
dc.date.issued | 2016-04-18 | - |
dc.identifier.issn | 1176-9092 | - |
dc.identifier.uri | http://hdl.handle.net/2445/127057 | - |
dc.description.abstract | Objective: To investigate the predictive value of functional impairment, chronic conditions, and laboratory biomarkers of aging for predicting 5-year mortality in the elderly aged 85 years. Methods: Predictive value for mortality of different geriatric assessments carried out during the OCTABAIX study was evaluated after 5 years of follow-up in 328 subjects aged 85 years. Measurements included assessment of functional status comorbidity, along with laboratory tests on vitamin D, cholesterol, CD4/CD8 ratio, hemoglobin, and serum thyrotropin. Results: Overall, the mortality rate after 5 years of follow-up was 42.07%. Bivariate analysis showed that patients who survived were predominantly female (P=0.02), and they showed a significantly better baseline functional status for both basic (P<0.001) and instrumental (P<0.001) activities of daily living (Barthel and Lawton index), better cognitive performance (Spanish version of the Mini-Mental State Examination) (P<0.001), lower comorbidity conditions (Charlson) (P<0.001), lower nutritional risk (Mini Nutritional Assessment) (P<0.001), lower risk of falls (Tinetti gait scale) (P<0.001), less percentage of heart failure (P=0.03) and chronic obstructive pulmonary disease (P=0.03), and took less chronic prescription drugs (P=0.002) than nonsurvivors. Multivariate Cox regression analysis identified a decreased score in the Lawton index (hazard ratio 0.86, 95% confidence interval: 0.78-0.91) and higher comorbidity conditions (hazard ratio 1.20, 95% confidence interval: 1.08-1.33) as independent predictors of mortality at 5 years in the studied population. Conclusion: The ability to perform instrumental activities of daily living and the global comorbidity assessed at baseline were the predictors of death, identified in our 85-year-old community-dwelling subjects after 5 years of follow-up. | - |
dc.format.extent | 8 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Dove Medical Press | - |
dc.relation.isformatof | Reproducció del document publicat a: https://doi.org/10.2147/CIA.S101447 | - |
dc.relation.ispartof | Clinical Interventions in Aging, 2016, vol. 11, p. 437-444 | - |
dc.relation.uri | https://doi.org/10.2147/CIA.S101447 | - |
dc.rights | cc-by-nc (c) Formiga Pérez, Francesc et al., 2016 | - |
dc.rights.uri | http://creativecommons.org/licenses/by-nc/3.0/es | - |
dc.source | Articles publicats en revistes (Ciències Clíniques) | - |
dc.subject.classification | Mortalitat | - |
dc.subject.classification | Geriatria | - |
dc.subject.classification | Envelliment | - |
dc.subject.classification | Comorbiditat | - |
dc.subject.other | Mortality | - |
dc.subject.other | Geriatrics | - |
dc.subject.other | Aging | - |
dc.subject.other | Comorbidity | - |
dc.title | Evidence of functional declining and global comorbidity measured at baseline proved to be the strongest predictors for long-term death in elderly community residents aged 85 years: a 5-year follow-up evaluation, the OCTABAIX study | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.identifier.idgrec | 676191 | - |
dc.date.updated | 2018-12-19T12:30:48Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 27143867 | - |
Appears in Collections: | Articles publicats en revistes (Ciències Clíniques) Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
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