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http://hdl.handle.net/2445/127394
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DC Field | Value | Language |
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dc.contributor.author | Terrazas Martínez, Montserrat | - |
dc.contributor.author | Sánchez, Dani | - |
dc.contributor.author | Battistini, Federica | - |
dc.contributor.author | Villegas, Núria | - |
dc.contributor.author | Brun-Heath, Isabelle | - |
dc.contributor.author | Orozco López, Modesto | - |
dc.date.accessioned | 2019-01-17T14:15:02Z | - |
dc.date.available | 2019-12-14T06:10:13Z | - |
dc.date.issued | 2018-12-14 | - |
dc.identifier.uri | http://hdl.handle.net/2445/127394 | - |
dc.description.abstract | Here we present 2shRNA, a shRNA-based nanobinder, which can simultaneously attack two therapeutic targets involved in drug resistance pathways and can additionally bind accessory molecules such as cell targeting peptides or fluorophores. We create 2shRNAs designed to specifically kill HER2+ breast cancer cells in the absence of a transfecting agent. | - |
dc.format.extent | 4 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | ca |
dc.publisher | Royal Society of Chemistry | ca |
dc.relation.isformatof | Versió postprint del document publicat a: https://doi.org/10.1039/C8CC08823C | - |
dc.relation.ispartof | Chemical Communications, 2018 | - |
dc.relation.uri | http://dx.doi.org/10.1039/C8CC08823C | - |
dc.rights | (c) Terrazas Martínez et al., 2018 | - |
dc.source | Articles publicats en revistes (Institut de Recerca Biomèdica (IRB Barcelona)) | - |
dc.subject.classification | Càncer de mama | - |
dc.subject.classification | Cèl·lules canceroses | - |
dc.subject.other | Breast cancer | - |
dc.subject.other | Cancer cells | - |
dc.title | A multifunctional toolkit for target-directed cancer therapy | ca |
dc.type | info:eu-repo/semantics/article | ca |
dc.date.updated | 2019-01-02T14:50:48Z | - |
dc.relation.projectID | info:eu-repo/grantAgreement/EC/H2020/823830/EU//BioExcel-2 | - |
dc.relation.projectID | info:eu-repo/grantAgreement/EC/FP7/291433/EU//SIMDNA | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
Appears in Collections: | Articles publicats en revistes (Institut de Recerca Biomèdica (IRB Barcelona)) |
Files in This Item:
File | Description | Size | Format | |
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Manuscript_Terrazas_Orozco_rev2_Dec5_2018.pdf | 2.86 MB | Adobe PDF | View/Open |
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