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https://hdl.handle.net/2445/127602| Title: | Removal of the chiral inductor from phenylglycinol-derived tricyclic lactams. Unexpected generation of chiral trans-hydrochromene lactones |
| Author: | Griera Farres, Rosa Pinto, Alexandre Fabregat, Robert Cots, Èric Bosch Cartes, Joan Amat Tusón, Mercedes |
| Keywords: | Alcaloides Lactames Síntesi asimètrica Alkaloids Lactams Asymmetric synthesis |
| Issue Date: | 2018 |
| Publisher: | Bentham Science Publishers |
| Abstract: | In the search for synthetic routes for the preparation of cis- and trans- decahydroquinolin-2- ones, a procedure for the generation of enantiopure trans-hydrochromene lactones, by treatment of (R)- phenylglycinol-derived oxazoloquinolone lactams with Na/liq. NH3 followed by acidification, has been developed. |
| Note: | Versió postprint del document publicat a: https://doi.org/10.2174/1570178615666171213143657 |
| It is part of: | Letters In Organic Chemistry, 2018, vol. 15, num. 5, p. 335-339 |
| URI: | https://hdl.handle.net/2445/127602 |
| Related resource: | https://doi.org/10.2174/1570178615666171213143657 |
| ISSN: | 1570-1786 |
| Appears in Collections: | Articles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica) Articles publicats en revistes (Institut de Biomedicina (IBUB)) |
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| File | Description | Size | Format | |
|---|---|---|---|---|
| 679217.pdf | 276.64 kB | Adobe PDF | View/Open |
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