Please use this identifier to cite or link to this item:
http://hdl.handle.net/2445/127746
Title: | Simultaneous cyclization and derivatization of peptides using cyclopentenediones |
Author: | Brun Cubero, Omar Archibald, L. J. Agramunt, Jordi Pedroso Muller, Enrique Grandas Sagarra, Anna |
Keywords: | Pèptids Cisteïna Estructura molecular Peptides Cysteine Molecular structure |
Issue Date: | 3-Mar-2017 |
Publisher: | American Chemical Society |
Abstract: | Unprotected linear peptides containing N-terminal cysteines and another cysteine residue can be simultaneously cyclized and derivatized using 2,2-disubstituted cyclopentenediones. High yields of cyclic peptide conjugates may be obtained in short reaction times using only a slight excess of the cyclopentenedione moiety under TEMPO catalysis and in the presence of LiCl. |
Note: | Versió postprint del document publicat a: https://doi.org/10.1021/acs.orglett.6b03825 |
It is part of: | Organic Letters, 2017, vol. 19, num. 5, p. 992-995 |
URI: | http://hdl.handle.net/2445/127746 |
Related resource: | https://doi.org/10.1021/acs.orglett.6b03825 |
ISSN: | 1523-7060 |
Appears in Collections: | Articles publicats en revistes (Química Inorgànica i Orgànica) |
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