Please use this identifier to cite or link to this item: http://hdl.handle.net/2445/127810
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dc.contributor.authorSolé Arjó, Daniel-
dc.contributor.authorPérez Janer, Ferran-
dc.contributor.authorGarcía-Rodeja Navarro, Yago-
dc.contributor.authorFernández Cadenas, Israel-
dc.date.accessioned2019-02-01T12:45:30Z-
dc.date.available2019-02-01T12:45:30Z-
dc.date.issued2017-01-03-
dc.identifier.issn1434-193X-
dc.identifier.urihttp://hdl.handle.net/2445/127810-
dc.description.abstractSulfonates, sulfonamides, and phosphonates have proven useful nucleophiles for palladium‐catalyzed intramolecular α‐arylation reactions leading to tetrahydroisoquinolines. Although the sulfonate α‐arylation reaction can be successfully combined in a domino process with a broad range of Michael acceptors, only vinyl sulfones can be used in Michael additions when starting from sulfonamides. No domino process was developed with the phosphonate derivative. DFT calculations were carried out to gain more insights into the experimental differences observed in the reactions involving these substrates.-
dc.format.extent7 p.-
dc.format.mimetypeapplication/pdf-
dc.language.isoeng-
dc.publisherWiley-VCH-
dc.relation.isformatofVersió postprint del document publicat a: https://doi.org/10.1002/ejoc.201601300-
dc.relation.ispartofEuropean Journal of Organic Chemistry, 2017, vol. 2017, num. 4, p. 799-805-
dc.relation.urihttps://doi.org/10.1002/ejoc.201601300-
dc.rights(c) Wiley-VCH, 2017-
dc.sourceArticles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica)-
dc.subject.classificationPal·ladi (Element químic)-
dc.subject.classificationCatàlisi-
dc.subject.classificationSulfamides-
dc.subject.classificationTeoria del funcional de densitat-
dc.subject.classificationSíntesi orgànica-
dc.subject.otherPalladium-
dc.subject.otherCatalysis-
dc.subject.otherSulfonamides-
dc.subject.otherDensity functionals-
dc.subject.otherOrganic synthesis-
dc.titleExploring Partners for the Domino α‐Arylation/Michael Addition Reaction Leading to Tetrahydroisoquinolines-
dc.typeinfo:eu-repo/semantics/article-
dc.typeinfo:eu-repo/semantics/acceptedVersion-
dc.identifier.idgrec667423-
dc.date.updated2019-02-01T12:45:31Z-
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess-
Appears in Collections:Articles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica)

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