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http://hdl.handle.net/2445/127829
Title: | Nucleic acid i-motif structures in analytical chemistry |
Author: | Alba, Juan Josep Sadurní, Anna Gargallo Gómez, Raimundo |
Keywords: | ADN Electroquímica Espectroscòpia DNA Electrochemistry Spectrum analysis |
Issue Date: | 3-Mar-2016 |
Publisher: | Taylor and Francis |
Abstract: | Under the appropriate experimental conditions of pH and temperature, cytosine-rich segments in DNA or RNA sequences may produce a characteristic folded structure known as an i-motif. Besides its potential role in vivo, which is still under investigation, this structure has attracted increasing interest in other fields due to its sharp, fast and reversible pH-driven conformational changes. This 'on/off' switch at molecular level is being used in nanotechnology and analytical chemistry to develop nanomachines and sensors, respectively. This paper presents a review of the latest applications of this structure in the field of chemical analysis. |
Note: | Versió postprint del document publicat a: https://doi.org/10.1080/10408347.2016.1143347 |
It is part of: | Critical Reviews in Analytical Chemistry, 2016, vol. 46, num. 5 |
URI: | http://hdl.handle.net/2445/127829 |
Related resource: | https://doi.org/10.1080/10408347.2016.1143347 |
ISSN: | 1040-8347 |
Appears in Collections: | Articles publicats en revistes (Enginyeria Química i Química Analítica) |
Files in This Item:
File | Description | Size | Format | |
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656924.pdf | 717.37 kB | Adobe PDF | View/Open |
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