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Title: Scaling the microrheology of living cells
Author: Fabry, Ben
Maksym, Geoffrey N.
Butler, James P.
Glogauer, Michael
Navajas Navarro, Daniel
Fredberg, Jeffrey J.
Keywords: Física mèdica
Equacions d'estat
Regla de les fases i equilibri
Medical physics
Equations of state
Phase rule and equilibrium
Issue Date: 2001
Publisher: The American Physical Society
Abstract: We report a scaling law that governs both the elastic and frictional properties of a wide variety of living cell types, over a wide range of time scales and under a variety of biological interventions. This scaling identifies these cells as soft glassy materials existing close to a glass transition, and implies that cytoskeletal proteins may regulate cell mechanical properties mainly by modulating the effective noise temperature of the matrix. The practical implications are that the effective noise temperature is an easily quantified measure of the ability of the cytoskeleton to deform, flow, and reorganize.
Note: Reproducció digital del document proporcionada per PROLA i
It is part of: Physical Review Letters, 2001, vol. 87, núm. 14, p. 148102-1-148102-4
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ISSN: 0031-9007
Appears in Collections:Articles publicats en revistes (Ciències Fisiològiques)

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