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http://hdl.handle.net/2445/128133
Title: | Association between mental disorders and subsequent adult onset asthma |
Author: | Alonso, Jordi Jonge, Peter de Lim, Carmen C. W. Aguilar Gaxiola, Sergio Bruffaerts, Ronny Caldas de Almeida, José Miguel Liu, Zhaorui O'Neill, Siobhan Stein, Dan J., 1962- Viana, Maria Carmen Al-Hamzawi, Ali Obaid Angermeyer, Matthias C. Borges, Guilherme Ciutan, Marius Girolamo, Giovanni de Fiestas, Fabian Haro Abad, Josep Maria Hu, Chiyi Kessler, Ronald C. Lépine, Jean Pierre Levinson, Daphna Nakamura, Yosikazu Posada Villa, José Wojtyniak, Bogdan J. Scott, Kate M. (Kate Margaret), 1960- |
Keywords: | Malalties mentals Asma Mental illness Asthma |
Issue Date: | Dec-2014 |
Publisher: | Elsevier Ltd |
Abstract: | Associations between asthma and anxiety and mood disorders are well established, but little is known about their temporal sequence. We examined associations between a wide range of DSM-IV mental disorders with adult onset of asthma and whether observed associations remain after mental comorbidity adjustments. METHODS: During face-to-face household surveys in community-dwelling adults (n = 52,095) of 19 countries, the WHO Composite International Diagnostic Interview retrospectively assessed lifetime prevalence and age at onset of 16 DSM-IV mental disorders. Asthma was assessed by self-report of physician's diagnosis together with age of onset. Survival analyses estimated associations between first onset of mental disorders and subsequent adult onset asthma, without and with comorbidity adjustment. RESULTS: 1860 adult onset (21 years+) asthma cases were identified, representing a total of 2,096,486 person-years of follow up. After adjustment for comorbid mental disorders several mental disorders were associated with subsequent adult asthma onset: bipolar (OR = 1.8; 95%CI 1.3-2.5), panic (OR = 1.4; 95%CI 1.0-2.0), generalized anxiety (OR = 1.3; 95%CI 1.1-1.7), specific phobia (OR = 1.3; 95%CI 1.1-1.6); post-traumatic stress (OR = 1.5; 95%CI 1.1-1.9); binge eating (OR = 1.8; 95%CI 1.2-2.9) and alcohol abuse (OR = 1.5; 95%CI 1.1-2.0). Mental comorbidity linearly increased the association with adult asthma. The association with subsequent asthma was stronger for mental disorders with an early onset (before age 21). CONCLUSIONS: A wide range of temporally prior mental disorders are significantly associated with subsequent onset of asthma in adulthood. The extent to which asthma can be avoided or improved among those with early mental disorders deserves study. |
Note: | Versió postprint del document publicat a: https://doi.org/10.1016/j.jpsychires.2014.09.007 |
It is part of: | Journal of Psychiatric Research, 2014, vol. 59, p. 179-188 |
URI: | http://hdl.handle.net/2445/128133 |
Related resource: | https://doi.org/10.1016/j.jpsychires.2014.09.007 |
ISSN: | 0022-3956 |
Appears in Collections: | Articles publicats en revistes (Medicina) |
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