1. Dipòsit Digital de la Universitat de Barcelona
  2. Recerca
  3. Farmacologia, Toxicologia i Química Terapèutica
  4. Articles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica)
Please use this identifier to cite or link to this item: http://hdl.handle.net/2445/128411
Full metadata record
DC FieldValueLanguage
dc.contributor.authorBosch, Caroline-
dc.contributor.authorLópez-Lledó, Pablo-
dc.contributor.authorBonjoch i Sesé, Josep-
dc.contributor.authorBradshaw, Ben-
dc.contributor.authorNieuwland, Pieter J.-
dc.contributor.authorBlanco-Ania, Daniel-
dc.contributor.authorRutjes, Floris P. J. T.-
dc.date.accessioned2019-02-19T11:20:04Z-
dc.date.available2019-02-19T11:20:04Z-
dc.date.issued2016-05-31-
dc.identifier.issn2062-249X-
dc.identifier.urihttp://hdl.handle.net/2445/128411-
dc.description.abstractAn Amberlite IR 120 H-promoted one-pot Fischer indolization from a cis-decahydroquinoline using a range of phenylhydrazines led to compounds with the pyrido[2,3-a]carbazole scaffold. The process may be conducted either in batch mode or in a continuous manner in a flow reactor. The stereochemical course of the Fischer indole reaction changed in going from using free phenylhydrazine to the corresponding hydrochloride in batch conditions, whereas, with the short reaction times in continuous flow, no changes due to isomerization processes were observed. Keywords: Fischer indole synthesis, one-pot synthesis, continuous-flow synthesis, sulfonic acid resin, immobilized reagents, pyrido[2,3-a]carbazoles-
dc.format.extent4 p.-
dc.format.mimetypeapplication/pdf-
dc.language.isoeng-
dc.relation.isformatofhttps://doi.org/10.1556/1846.2016.00016-
dc.relation.ispartofJournal Of Flow Chemistry, 2016, vol. 6, num. 3, p. 240-243-
dc.relation.urihttps://doi.org/10.1556/1846.2016.00016-
dc.rights, 2016-
dc.sourceArticles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica)-
dc.subject.classificationSíntesi en fase sólida-
dc.subject.classificationCompostos heterocíclics-
dc.subject.classificationÀcids orgànics-
dc.subject.classificationSíntesi orgànica-
dc.subject.otherSolid-phase synthesis-
dc.subject.otherHeterocyclic compounds-
dc.subject.otherOrganic acids-
dc.subject.otherOrganic synthesis-
dc.titleFischer indole reaction in batch and flow employing a sulfonic acid resin: synthesis of pyrido[2,3-a]carbazoles-
dc.typeinfo:eu-repo/semantics/article-
dc.identifier.idgrec666640-
dc.date.updated2019-02-19T11:20:04Z-
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess-
Appears in Collections:Articles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica)
Articles publicats en revistes (Institut de Biomedicina (IBUB))

Files in This Item:
File Description SizeFormat 
666640.pdf3.64 MBAdobe PDFView/Open
Show simple item record


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.