Please use this identifier to cite or link to this item:
http://hdl.handle.net/2445/128419
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DC Field | Value | Language |
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dc.contributor.author | Bosch, Caroline | - |
dc.contributor.author | Fiser, Bela | - |
dc.contributor.author | Gómez-Bengoa, Enrique | - |
dc.contributor.author | Bradshaw, Ben | - |
dc.contributor.author | Bonjoch i Sesé, Josep | - |
dc.date.accessioned | 2019-02-19T12:07:13Z | - |
dc.date.available | 2019-02-19T12:07:13Z | - |
dc.date.issued | 2015-09-25 | - |
dc.identifier.issn | 1523-7060 | - |
dc.identifier.uri | http://hdl.handle.net/2445/128419 | - |
dc.description.abstract | A unified strategy for the synthesis of the cisphlegmarine group of alkaloids is presented, leading to the first synthesis of serratezomine E (1) as well as the putative structure of huperzine N (2). A contrasteric hydrogenation method was developed based on the use of Wilkinson's catalyst, which allowed the facial selectivity of standard hydrogenation to be completely overturned. Calculations were performed to determine the mechanism, and structures for huperzines M and N are reassigned. | - |
dc.format.extent | 4 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | American Chemical Society | - |
dc.relation.isformatof | Versió postprint del document publicat a: https://doi.org/10.1021/acs.orglett.5b02581 | - |
dc.relation.ispartof | Organic Letters, 2015, vol. 17, num. 20, p. 5084-5087 | - |
dc.relation.uri | https://doi.org/10.1021/acs.orglett.5b02581 | - |
dc.rights | (c) American Chemical Society , 2015 | - |
dc.source | Articles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica) | - |
dc.subject.classification | Alcaloides | - |
dc.subject.classification | Compostos heterocíclics | - |
dc.subject.classification | Síntesi orgànica | - |
dc.subject.classification | Productes naturals | - |
dc.subject.other | Alkaloids | - |
dc.subject.other | Heterocyclic compounds | - |
dc.subject.other | Organic synthesis | - |
dc.subject.other | Natural products | - |
dc.title | Approach to cis-Phlegmarine Alkaloids via Stereodivergent Reduction: Total Synthesis of (+)-Serratezomine E and Putative Structure of (−)-Huperzine N | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/acceptedVersion | - |
dc.identifier.idgrec | 666641 | - |
dc.date.updated | 2019-02-19T12:07:14Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 26406568 | - |
Appears in Collections: | Articles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica) Articles publicats en revistes (Institut de Biomedicina (IBUB)) |
Files in This Item:
File | Description | Size | Format | |
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666641.pdf | 843.47 kB | Adobe PDF | View/Open |
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