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Title: The effect of pulmonary surfactant on the in vitro activity of Iclaprim against common respiratory bacterial pathogens
Author: Huang, David B.
Duncan, Leonard R.
Flamm, Robert K.
Dryden, Matthew
Corey, G. Ralph
Wilcox, Mark H.
Torres Martí, Antoni
File, Thomas M.
Keywords: Pneumònia
Bacteris patògens
Efecte dels medicaments sobre els microorganismes
Pathogenic bacteria
Effect of drugs on microorganisms
Issue Date: Jan-2018
Publisher: Elsevier B.V.
Abstract: The in vitro antimicrobial activity of iclaprim, a novel diaminopyrimidine, against common respiratory bacteria remained unchanged in the presence of pulmonary surfactant (Survanta®) at concentrations that greatly antagonized the antimicrobial activity of daptomycin. These results indicate that iclaprim could be a potential treatment for pneumonia caused by susceptible and multidrug resistant bacteria.
Note: Versió postprint del document publicat a:
It is part of: Diagnostic Microbiology and Infectious Disease, 2018, vol. 90, num. 1, p. 64-66
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ISSN: 0732-8893
Appears in Collections:Articles publicats en revistes (Medicina)
Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer)

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