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http://hdl.handle.net/2445/132145| Title: | The effect of pulmonary surfactant on the in vitro activity of Iclaprim against common respiratory bacterial pathogens |
| Author: | Huang, David B. Duncan, Leonard R. Flamm, Robert K. Dryden, Matthew Corey, G. Ralph Wilcox, Mark H. Torres Martí, Antoni File, Thomas M. |
| Keywords: | Pneumònia Bacteris patògens Efecte dels medicaments sobre els microorganismes Pneumonia Pathogenic bacteria Effect of drugs on microorganisms |
| Issue Date: | Jan-2018 |
| Publisher: | Elsevier B.V. |
| Abstract: | The in vitro antimicrobial activity of iclaprim, a novel diaminopyrimidine, against common respiratory bacteria remained unchanged in the presence of pulmonary surfactant (Survanta®) at concentrations that greatly antagonized the antimicrobial activity of daptomycin. These results indicate that iclaprim could be a potential treatment for pneumonia caused by susceptible and multidrug resistant bacteria. |
| Note: | Versió postprint del document publicat a: https://doi.org/10.1016/j.diagmicrobio.2017.09.011 |
| It is part of: | Diagnostic Microbiology and Infectious Disease, 2018, vol. 90, num. 1, p. 64-66 |
| URI: | http://hdl.handle.net/2445/132145 |
| Related resource: | https://doi.org/10.1016/j.diagmicrobio.2017.09.011 |
| ISSN: | 0732-8893 |
| Appears in Collections: | Articles publicats en revistes (Medicina) Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer) |
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