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Title: Full-term pregnancy in breast cancer survivor with fertility preservation: A case report and review of literature
Author: Garrido-Marín, Marta
Argacha, Pedro Maria
Fernández, Luís
Molfino, Florencia
Martínez Soler, Fina
Tortosa i Moreno, Avelina
Giménez Bonafé, Pepita
Keywords: Càncer de mama
Fecundació in vitro humana
Ressenyes sistemàtiques (Investigació mèdica)
Breast cancer
Human in vitro fertilization
Systematic reviews (Medical research)
Issue Date: 6-Jan-2019
Abstract: A 43-year-old woman with an associated history of gynecological pathology and breast cancer with only one cryopreserved embryo wished to be a mother. Several factors that influenced the success of the pregnancy in this case were analyzed. Favorable factors included: triple positive breast cancer [positive hormone receptors and positive human epidermal growth factor receptor 2], which is more hormosensitive and chemosensitive; absence of metastasis; correct endometrium preparation; and the patient's optimistic attitude and strict health habits. In contrast, the factors against success were: breast cancer; adjuvant breast cancer therapy gonadotoxicity; the age of the patient (> 40-year-old); endometriosis; ovarian cyst; hydrosalpinx; submucosal fibroids and the respective associated surgery done for the above-mentioned pathology (all resolved prior to the embryo transfer); and a low quantity of ovules (low ovarian reserve) after ovarian stimulation. This is a very special clinical case of a patient with theoretically low pregnancy success probability due to the consecutive accumulation of gynecological and oncological pathologies, who nonetheless became pregnant and delivered a full-term infant and was able to provide adequate breastfeeding.
Note: Reproducció del document publicat a:
It is part of: World Journal Of Clinical Cases, 2019, vol. 7, num. 1, p. 58-68
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ISSN: 2307-8960
Appears in Collections:Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))
Articles publicats en revistes (Ciències Fisiològiques)
Articles publicats en revistes (Infermeria Fonamental i Clínica)

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