Please use this identifier to cite or link to this item:
http://hdl.handle.net/2445/134162
Title: | Cell Migration Driven by Cooperative Substrate Deformation Patterns |
Author: | Angelini, Thomas E. Hannezo, Edouard Trepat Guixer, Xavier Fredberg, Jeffrey J. Weitz, David A. |
Keywords: | Cèl·lules eucariotes Migració cel·lular Eukaryotic cells Cell migration |
Issue Date: | 23-Apr-2010 |
Publisher: | American Physical Society |
Abstract: | Most eukaryotic cells sense and respond to the mechanical properties of their surroundings. This can strongly influence their collective behavior in embryonic development, tissue function, and wound healing. We use a deformable substrate to measure collective behavior in cell motion due to substrate mediated cell-cell interactions. We quantify spatial and temporal correlations in migration velocity and substrate deformation, and show that cooperative cell-driven patterns of substrate deformation mediate long-distance mechanical coupling between cells and control collective cell migration. |
Note: | Reproducció del document publicat a: https://doi.org/10.1103/PhysRevLett.104.168104 |
It is part of: | Physical Review Letters, 2010, vol. 104, num. 16, p. 168104 |
URI: | http://hdl.handle.net/2445/134162 |
Related resource: | https://doi.org/10.1103/PhysRevLett.104.168104 |
ISSN: | 0031-9007 |
Appears in Collections: | Articles publicats en revistes (Institut de Bioenginyeria de Catalunya (IBEC)) Articles publicats en revistes (Biomedicina) |
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613165.pdf | 793.69 kB | Adobe PDF | View/Open |
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