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Title: | Novel cyclometallated iridium catalysts for asymmetric hydrogenation of N-methyl and N-phenyl imines |
Other Titles: | Nous catalitzadors ciclometal·lats d’iridi per hidrogenacions asimètriques d’N-metil i N-fenil imines |
Author: | Fernández Sabaté, Marc |
Director/Tutor: | Verdaguer i Espaulella, Xavier Salomó i Prat, Ernest Rojo Solé, Josep Ma. |
Keywords: | Iridi Hidrogenació Treballs de fi de grau Iridium Hydrogenation Bachelor's theses |
Issue Date: | Jun-2019 |
Abstract: | In this work, three acetophenone N-phenyl imine derivatives functionalized in the para position have been prepared and cyclometallated to Ir-MaxPHOX catalyst. One of the additives has a hydrogen bond acceptor group, while the others have bulky substituents. The behavior of these compounds in asymmetric hydrogenation of acetophenone N-methyl and N-phenyl imine substrates has been studied. The additive containing a hydrogen bond acceptor provided better enantioselectivity than the others. This reinforces the hypothesis that a hydrogen bond interaction between the catalyst and the substrate would increase the selectivity. Additives with bulky substituents provided worse results, probably due to steric hindrance, decreasing the selectivity |
Note: | Treballs Finals de Grau de Química, Facultat de Química, Universitat de Barcelona, Any: 2019, Tutors: Xavier Verdaguer Espaulella, Ernest Salomó i Prat, Josep Mª Rojo Solé |
URI: | http://hdl.handle.net/2445/138499 |
Appears in Collections: | Treballs Finals de Grau (TFG) - Química |
Files in This Item:
File | Description | Size | Format | |
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TFG_QU Fernandez Sabaté, Marc.pdf | 700.07 kB | Adobe PDF | View/Open |
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