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http://hdl.handle.net/2445/138618
Title: | Epigenetics in the eye: an overview of the most relevant ocular diseases |
Author: | Alkozi, Hanan Awad Franco Fernández, Rafael Pintor, Jesús J. |
Keywords: | Epigenètica Manifestacions oculars de les malalties Epigenetics Ocular manifestations of general diseases |
Issue Date: | 12-Oct-2017 |
Publisher: | Frontiers Media |
Abstract: | Sight for mammals is one of the most appreciated senses. In humans there are several factors that contribute to the increment in all kind of eye diseases. This mini-review will focus on some diseases whose prevalence is steadily increasing year after year for non-genetic reasons, namely cataracts, dry eye, and glaucoma. Aging, diet, inflammation, drugs, oxidative stress, seasonal and circadian style-of-live changes are impacting on disease prevalence by epigenetics factors, defined as stable heritable traits that are not explained by changes in DNA sequence. The mini-review will concisely show the data showing epigenetics marks in these diseases and on how knowledge on the epigenetic alterations may guide therapeutic approaches to have a healthy eye. |
Note: | Reproducció del document publicat a: https://doi.org/10.3389/fgene.2017.00144 |
It is part of: | Frontiers In Genetics, 2017, vol. 8, p. 144 |
URI: | http://hdl.handle.net/2445/138618 |
Related resource: | https://doi.org/10.3389/fgene.2017.00144 |
ISSN: | 1664-8021 |
Appears in Collections: | Articles publicats en revistes (Bioquímica i Biomedicina Molecular) |
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674719.pdf | 605.8 kB | Adobe PDF | View/Open |
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