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http://hdl.handle.net/2445/141947
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DC Field | Value | Language |
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dc.contributor.author | Carmona Dalmases, Gerard | - |
dc.contributor.author | Roca, Emma | - |
dc.contributor.author | Guerrero, Mario | - |
dc.contributor.author | Cussó Fresquet, M. Roser | - |
dc.contributor.author | Bárcena, Cristina | - |
dc.contributor.author | Mateu Serra, Mercè | - |
dc.contributor.author | Cadefau Surroca, Joan Aureli | - |
dc.date.accessioned | 2019-10-09T13:41:58Z | - |
dc.date.available | 2020-03-05T06:10:19Z | - |
dc.date.issued | 2019-03-05 | - |
dc.identifier.issn | 0172-4622 | - |
dc.identifier.uri | http://hdl.handle.net/2445/141947 | - |
dc.description.abstract | Consequences of running mountain races on muscle damage were investigated by analysing serum muscle enzymes and fibre-type-specific sarcomere proteins. We studied 10 trained amateur and 6 highly trained runners who ran a 35 km and 55 km mountain trail race (MTR), respectively. Levels of creatine kinase (CK), CK-MB isoform (CK-MB), sarcomeric mitochondrial CK (sMtCK), transaminases (AST and ALT), cardiac troponin I (cTnI) and fast (FM) and slow myosin (SM) isoforms, were assessed before, 1 h, 24 h and 48 h after the beginning of MTR. Significant SM increases were found at 24 h in the 55 km group. Levels of CK, CK-MB, AST and cTnI were significantly elevated in both groups following MTR, but in the 55 km group they tended to stabilize in at 48 h. Using pooled data, time-independent serum peaks of SM and CK-MB were significantly correlated. Moreover, concentration of sMtCK was significantly elevated at 1 and 24 h after the race in the 35 km group. Although training volume could confer protection on the mitochondria, the increase in serum CK-MB and SM in the 55 km group might be related to damage to the contractile apparatus type I fibres. Competing in long-distance MTRs might be related to deeper type I muscle fibre damage, even in highly trained individuals. | - |
dc.format.extent | 10 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Georg Thieme Verlag | - |
dc.relation.isformatof | Reproducció del document publicat a: https://doi.org/10.1055/a-0808-4692 | - |
dc.relation.ispartof | International Journal of Sports Medicine, 2019, vol. 40, num. 4, p. 253-262 | - |
dc.relation.uri | https://doi.org/10.1055/a-0808-4692 | - |
dc.rights | (c) Georg Thieme Verlag, 2019 | - |
dc.source | Articles publicats en revistes (Biomedicina) | - |
dc.subject.classification | Marcadors bioquímics | - |
dc.subject.classification | Exercici | - |
dc.subject.classification | Fisiologia de l'exercici | - |
dc.subject.classification | Cèl·lules musculars | - |
dc.subject.other | Biochemical markers | - |
dc.subject.other | Exercise | - |
dc.subject.other | Exercise physiology | - |
dc.subject.other | Muscle cells | - |
dc.title | Fibre-type-specific and Mitochondrial Biomarkers of Muscle Damage after Mountain Races | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.identifier.idgrec | 691898 | - |
dc.date.updated | 2019-10-09T13:41:58Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 30836391 | - |
Appears in Collections: | Articles publicats en revistes (Biomedicina) |
Files in This Item:
File | Description | Size | Format | |
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691898.pdf | 3.06 MB | Adobe PDF | View/Open |
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