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Title: New antimicrobial approaches to gram positive respiratory infections
Author: Liapikou, Adamantia
Cillóniz, Catia
Mensa Pueyo, Josep
Torres Martí, Antoni
Keywords: Infeccions respiratòries
Infeccions per pneumococs
Respiratory infections
Pneumococcal Infections
Issue Date: 27-May-2014
Publisher: Elsevier
Abstract: Nowadays, we face growing resistance among gram-positive and gram-negative pathogens that cause respiratory infection in the hospital and in the community. The spread of penicillin- and macrolide-resistant pneumococci, Community-acquired methicillin-resistant staphylococcus aureus (Ca-MRSA), the emergence of glycopeptide-resistant staphylococci underline the need for underline the need for therapeutic alternatives. A number of new therapeutic agents, with activity against the above Gram (+) respiratory pathogens, as ceftaroline, ceftopibrole, telavancin, tedizolid have become available, either in clinical trials or have been approved for clinical use. Especially, the development of new oral antibiotics, as nemonaxacin, omadacyclin, cethromycin and solithromycin will give a solution to the lack of oral drugs for outpatient treatment. In the future the clinician needs to optimize the use of old and new antibiotics to treat gram (+) respiratory serious infections.
Note: Versió postprint del document publicat a:
It is part of: Pulmonary Pharmacology and Therapeutics, 2014, vol. 32, p. 13-143
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ISSN: 1094-5539
Appears in Collections:Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer)
Articles publicats en revistes (Medicina)

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