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DC Field | Value | Language |
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dc.contributor.author | Flores, José Carlos | - |
dc.contributor.author | Gracia Lavedan, Esther | - |
dc.contributor.author | Benavente, Yolanda | - |
dc.contributor.author | Amiano, Pilar | - |
dc.contributor.author | Romaguera, Dora | - |
dc.contributor.author | Costas, Laura | - |
dc.contributor.author | Robles, Claudia | - |
dc.contributor.author | González Barca, Eva | - |
dc.contributor.author | Banda, Esmeralda de la | - |
dc.contributor.author | Alonso Sanz, Esther | - |
dc.contributor.author | Aymerich Gregorio, Marta | - |
dc.contributor.author | Campo Güerri, Elias | - |
dc.contributor.author | Dierssen Sotos, Trinidad | - |
dc.contributor.author | Marcos Gragera, Rafael | - |
dc.contributor.author | Rodriguez Suarez, Marta María | - |
dc.contributor.author | Solans, Marta | - |
dc.contributor.author | Gimeno Vázquez, Eva | - |
dc.contributor.author | Garcia Martin, Paloma | - |
dc.contributor.author | Aragonès Sanz, Núria | - |
dc.contributor.author | Shivappa, Nitin | - |
dc.contributor.author | Hébert, James R. | - |
dc.contributor.author | Pollán, Marina | - |
dc.contributor.author | Kogevinas, Manolis | - |
dc.contributor.author | Sanjosé Llongueras, Silvia de | - |
dc.contributor.author | Castaño-Vinyals, Gemma | - |
dc.contributor.author | Casabonne, Delphine | - |
dc.date.accessioned | 2020-01-16T12:49:33Z | - |
dc.date.available | 2020-01-16T12:49:33Z | - |
dc.date.issued | 2019-12-23 | - |
dc.identifier.uri | http://hdl.handle.net/2445/148017 | - |
dc.description.abstract | Chronic inflammation plays a role in the development of chronic lymphocytic leukaemia (CLL), and diet might modulate chronic inflammation. This study aims to evaluate the association between the dietary inflammatory index (DII®) and CLL. A total of 366 CLL cases and 1643 controls of the Spanish multicase-control (MCC) Spain study were included. The inflammatory potential of the diet was assessed using the energy-adjusted dietary inflammatory index (E-DII) based on 30 items from a validated semi-quantitative food frequency questionnaire. Odds ratios (OR) and 95% confidence intervals (CI) were estimated using logistic regression models controlling for potential confounders. Overall, a modest, non-statistically significant, positive association was observed between CLL and E-DII scores (OR for a one-unit increase in E-DII: 1.05 (CI 95%: 0.99, 1.12), p-value = 0.09 and by tertiles: ORT2vsT1: 1.20 (CI 95%: 0.90, 1.59); OR T3vsT1: 1.21 (CI 95%: 0.90, 1.62), p trend = 0.21). These results were independent from disease severity (p-het: 0.70), time from diagnosis (p-het: 0.67) and CLL treatment received (p-het: 0.56). No interactions were detected. In conclusion, the consumption of a diet with high pro-inflammatory components was not significantly associated with CLL. Changes towards a more pro-inflammatory dietary pattern in younger generations not included here warrant future research. | - |
dc.format.extent | 15 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | MDPI AG | - |
dc.relation.isformatof | Reproducció del document publicat a: https://doi.org/10.3390/nu12010048 | - |
dc.relation.ispartof | Nutrients, 2019, vol. 12, num. 1 | - |
dc.relation.uri | https://doi.org/10.3390/nu12010048 | - |
dc.rights | cc by (c) Flores et al., 2019 | - |
dc.rights.uri | http://creativecommons.org/licenses/by/3.0/es/ | - |
dc.source | Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) | - |
dc.subject.classification | Leucèmia limfocítica crònica | - |
dc.subject.classification | Càncer | - |
dc.subject.other | Chronic lymphocytic leukemia | - |
dc.subject.other | Cancer | - |
dc.title | The Dietary Inflammatory Index and Chronic Lymphocytic Leukaemia in the MCC Spain Study | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.date.updated | 2020-01-15T14:10:58Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 31878004 | - |
Appears in Collections: | Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer) Articles publicats en revistes (ISGlobal) Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
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nutrients-12-00048-v2.pdf | 720.27 kB | Adobe PDF | View/Open |
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