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http://hdl.handle.net/2445/149433
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DC Field | Value | Language |
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dc.contributor.author | Hueso Val, Miguel | - |
dc.contributor.author | Ramon, Laura de | - |
dc.contributor.author | Navarro, Estanis | - |
dc.contributor.author | Ripoll Llagostera, Èlia | - |
dc.contributor.author | Cruzado, Josep Ma. | - |
dc.contributor.author | Grinyó Boira, Josep M. | - |
dc.contributor.author | Torras Ambròs, Joan | - |
dc.date.accessioned | 2020-02-06T12:07:29Z | - |
dc.date.available | 2020-02-06T12:07:29Z | - |
dc.date.issued | 2016-12 | - |
dc.identifier.issn | 2352-3409 | - |
dc.identifier.uri | http://hdl.handle.net/2445/149433 | - |
dc.description.abstract | Data presented in this Data in Brief article correspond to the article 'in vivo' silencing of CD40 reduces progression of experimental atherogenesis through a NFκB/miR-125b axis and reveals new potential mediators in the pathogenesis of atherosclerosis' (M. Hueso, L. De Ramon, E. Navarro, E. Ripoll, J.M. Cruzado, J.M. Grinyo, J. Torras, 2016) [1]. Here, we describe the validation of the silencing of CD40 expression with a specific siRNA in ApoE−/− mouse aortas, and its systemic effects on splenic lymphocytic subpopulations as well as on the infiltration of aortic intima by F4/80+, galectin-3+ macrophages or by NF-κB+ cells. We also show the output of a Gene Ontology and TLDA analysis which allowed the detection of potential mediators of atherosclerosis progression. We provide the scientific community with a set of genes whose expression is increased during atherosclerosis progression but downregulated upon CD40 silencing. | - |
dc.format.extent | 8 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Elsevier | - |
dc.relation.isformatof | Reproducció del document publicat a: https://doi.org/10.1016/j.dib.2016.11.045 | - |
dc.relation.ispartof | Data in Brief, 2016, vol. 9, p. 1105-1112 | - |
dc.relation.uri | https://doi.org/10.1016/j.dib.2016.11.045 | - |
dc.rights | cc-by (c) Hueso Val, Miguel et al., 2016 | - |
dc.rights.uri | http://creativecommons.org/licenses/by/3.0/es | - |
dc.source | Articles publicats en revistes (Ciències Clíniques) | - |
dc.subject.classification | RNA | - |
dc.subject.classification | Macròfags | - |
dc.subject.classification | Aterosclerosi | - |
dc.subject.classification | Ratolins (Animals de laboratori) | - |
dc.subject.other | RNA | - |
dc.subject.other | Macrophages | - |
dc.subject.other | Atherosclerosis | - |
dc.subject.other | Mice (Laboratory animals) | - |
dc.title | Datasets for the validation of the 'in vivo' siRNA-silencing of CD40 and for the detection of new markers of aterosclerosis progression in ApoE-deficient mice | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.identifier.idgrec | 666378 | - |
dc.date.updated | 2020-02-06T12:07:29Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 27924297 | - |
Appears in Collections: | Articles publicats en revistes (Ciències Clíniques) Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
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File | Description | Size | Format | |
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666378.pdf | 5.59 MB | Adobe PDF | View/Open |
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