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http://hdl.handle.net/2445/154277
Title: | MDR/XDR-TB management of patients and contacts: challenges facing the new decade. The 2020 clinical update by the Global Tuberculosis Network |
Author: | Migliori, Giovanni Battista Tiberi, Simon Zumla, Alimuddin Petersen, Eskild Muhwa Chakaya, Jeremiah Wejse, Christian Muñoz Torrico, Marcela Duarte, Raquel Alffenaar, Jan-Willem Schaaf, H. Simon Marais, Ben J. Cirillo, Daniela Maria Alagna, Riccardo Rendon, Adrian Pontali, Emanuele Piubello, Alberto Figueroa, José Ferlazzo, Gabriella García-Basteiro, Alberto L. Centis, Rosella Visca, Dina Ambrosio, Lia D’ Sotgiu, Giovanni Global Tuberculosis Network |
Keywords: | Tuberculosi Diagnòstic Tuberculosis Diagnosis |
Issue Date: | 1-Mar-2020 |
Publisher: | Elsevier |
Abstract: | The continuous flow of new research articles on MDR-TB diagnosis, treatment, prevention and rehabilitation requires frequent update of existing guidelines. This review is aimed at providing clinicians and public health staff with an updated and easy-to-consult document arising from consensus of Global Tuberculosis Network (GTN) experts. The core published documents and guidelines have been reviewed including the recently published MDR-TB WHO rapid advice and ATS/CDC/ERS/IDSA guidelines. After a rapid review of epidemiology and risk factors, the clinical priorities on MDR-TB diagnosis (including whole genome sequencing and drug-susceptibility testing interpretations) and treatment (treatment design and management, TB in children) are discussed. Furthermore, the review comprehensively describes the latest information on contact tracing and LTBI management in MDR-TB contacts, while providing guidance on post-treatment functional evaluation and rehabilitation of TB sequelae, infection control and other public health priorities. |
Note: | Reproducció del document publicat a: http://dx.doi.org/10.1016/j.ijid.2020.01.042 |
It is part of: | International Journal of Infectious Diseases, 2020, vol. 92, p. S15-S25 |
URI: | http://hdl.handle.net/2445/154277 |
Related resource: | http://dx.doi.org/10.1016/j.ijid.2020.01.042 |
ISSN: | 1201-9712 |
Appears in Collections: | Articles publicats en revistes (ISGlobal) |
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BattistaMiglioriG_Int_J_Infect_Dis_2020.pdf | 1.36 MB | Adobe PDF | View/Open |
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