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Title: Determinants of time to institutionalisation and related healthcare and societal costs in a community-based cohort of patients with Alzheimer's disease dementia.
Author: Belger, Mark
Haro Abad, Josep Maria
Reed, Catherine
Happich, Michael
Argimón Pallás, José M.
Bruno, Giuseppe
Dodel, Richard
Jones, Roy W.
Vellas, Bruno
Wimo, Anders
Keywords: Malaltia d'Alzheimer
Malalties neurodegeneratives
Salut pública
Alzheimer's disease
Neurodegenerative Diseases
Public health
Issue Date: Apr-2019
Publisher: Springer Verlag
Abstract: OBJECTIVES: To examine the costs of caring for community-dwelling patients with Alzheimer's disease (AD) dementia in relation to the time to institutionalisation. METHODS: GERAS was a prospective, non-interventional cohort study in community-dwelling patients with AD dementia and their caregivers in three European countries. Using identified factors associated with time to institutionalisation, models were developed to estimate the time to institutionalisation for all patients. Estimates of monthly total societal costs, patient healthcare costs and total patient costs (healthcare and social care together) prior to institutionalisation were developed as a function of the time to institutionalisation. RESULTS: Of the 1495 patients assessed at baseline, 307 (20.5%) were institutionalised over 36 months. Disease severity at baseline [based on Mini-Mental State Examination (MMSE) scores] was associated with risk of being institutionalised during follow up (p < 0.001). Having a non-spousal informal caregiver was associated with a faster time to institutionalisation (944 fewer days versus having a spousal caregiver), as was each one-point worsening in baseline score of MMSE, instrumental activities of daily living and behavioural disturbance (67, 50 and 30 fewer days, respectively). Total societal costs, total patient costs and, to a lesser extent, patient healthcare-only costs were associated with time to institutionalisation. In the 5 years pre-institutionalisation, monthly total societal costs increased by more than £1000 (¿1166 equivalent for 2010) from £1900 to £3160 and monthly total patient costs almost doubled from £770 to £1529. CONCLUSIONS: Total societal costs and total patient costs rise steeply as community-dwelling patients with AD dementia approach institutionalisation.
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It is part of: European Journal of Health Economics, 2018, vol. 20, num. 3, p. 343-355
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ISSN: 1618-7598
Appears in Collections:Articles publicats en revistes (Medicina)

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